Traumatic brain injury reagents

Accelerate your study of traumatic brain injury (TBI) with the ultimate catalog of gold-standard recombinant antibodies, immunoassays and bioactive proteins. Industry-leading validation guarantees the specificity of our reagents so you can unpack the complex cascades associated with TBI and focus on your targets of interest. Recombinant technology guarantees accurate, consistent results first time, every time and over time.

Explore our curated catalog of reagents to GFAP, UCHL1, S100B, NFL and more all in one place.

Neuronal and synaptic injury

The different types of damage present– axonal, neuronal body, dendritic, synaptic, and even glial and oligodendrocyte –cause complex overall pathophysiology. This complexity demands precise reagents that bind specifically to injury regions to give an accurate picture of injury type and extent.

Our broad range of recombinant antibodies offers superior sensitivity to various targets involved in TBI pathology, including GFAP, S100B and BDNF. Our premium antibodies are extensively validated across applications and reactive species, including human. Where relevant, we test our antibodies in sample types like brain tissue or neuronal cell lines to ensure specificity to your research.

Explore our curated catalog and find the right reagent for your target of interest.

Product highlights

abcam:product-category/primary-antibodies

ab108319

Anti-BDNF antibody [EPR1292]

• Top-cited reagent to BDNF available (>600 citations)
• Reacts with human, mouse and rat samples
• Validated in IHC-P, IHC-Fr, WB, ICC/IF and flow cytometry (intra)
• Validated in human brain tissue

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abcam:product-category/primary-antibodies

ab109390

Anti-Tau (phospho S396) antibody [EPR2731]

• The most-cited antibody against phospho Tau S396
• Validated in AD patient samples
• Carrier-free and conjugated formats available

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BBB disruption, inflammation and excitotoxicity

TBI development is exacerbated by disruption to the blood-brain barrier, the onset of neuroinflammation, and glutamate excitotoxicity. Our catalog includes highly-validated recombinant antibodies against targets relating to these events, including MMP9, Caspase-3 and FBG.

Product highlights

abcam:product-category/primary-antibodies

ab283575

Anti-MMP9 antibody [RM1020]

• Recombinant multiclonal antibody
• >50 citations
• Validated in ICC/IF, IP, flow cytometry (intra), WB, I-ELISA, IHC-Fr, IHC-P)

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abcam:product-category/primary-antibodies

ab32351

Anti-Caspase-3 antibody [E87]

• >400 citations
• Knock-out validated
• Suitable for IHC-P, IP, WB, ICC/IF
• Reacts with human samples

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Bioactive and recombinant proteins

Our premium bioactive proteins allow you to interrogate pathways with ease. Our proteins are mammalian-expressed, guarantee high (>95%) purity and ultra-low (<1 EU/μg) endotoxins, and are manufactured in an animal-free process. Our in-house production and comprehensive validation ensure optimal bioactivity, so you can get the same results with less reagent.

Product highlights

abcam:product-category/proteins-and-peptides

ab222178

Recombinant human BDNF protein (Animal Free)

• Animal-free
• Suitable for functional studies, SDS-PAGE and HPLC
• Low endotoxin (<1 EU/μg)

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abcam:product-category/proteins-and-peptides

ab200489

Recombinant human S100 beta protein

• Suitable for functional studies
• Low endotoxin (<1 EU/μg)
• High purity (>95%)

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ELISA kits to study fluid biomarkers

Save time and get consistent results with our SimpleStep ELISA® kits. Their simple, single-wash protocol saves hours at the bench without sacrificing performance: they’re powered by our premium recombinant antibodies so you’ll get accurate results time after time.

To support high-throughput research, we offer growing numbers of our kits in 10-pack sizes and a 384-well format, allowing you to get 300% more from your precious samples while using only a quarter of the sample volume.

Browse our range and discover our solutions for key TBI biomarkers.

Product highlights

abcam:product-category/elisa-kits

ab288182

NEFL ELISA Kit

• Reacts with human, mouse and rat samples
• Large working range: 93.75-6000 pg/mL

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abcam:product-category/elisa-kits

ab314846

Human S100B ELISA Kit – Extracellular

• Validated with human CSF and serum samples

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