Active human Tollip peptide is a Synthetic blocking peptide. Suitable for BL.
Tag free
BL
Yes
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application BL | Reactivity Reacts | Dilution info - | Notes - |
Select an associated product type
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Toll-interacting protein, TOLLIP
Active human Tollip peptide is a Synthetic blocking peptide. Suitable for BL.
Tag free
BL
Yes
Blocking the activity of TOLLIP antibody.
No
Human
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA
Liquid
ab40023 is a crude synthetic peptide, purity range from 60-70%. The sequence is proprietary.
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity (PubMed:11751856). Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).
Belongs to the tollip family.
Phosphorylated by IRAK1 upon stimulation by IL-1 or microbial products.
Blue Ice
-20°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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