Skip to main content

Active Poly (Glu, Tyr) peptide is a Synthetic peptide. >95% purity and suitable for FuncS.

Be the first to review this product! Submit a review

Publications

  • Communications chemistry 5:52022
    Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors.
    Applications:
    Unspecified application
    Reactive species:
    Unspecified reactive species
    Lingzhi Qu,Xiaojuan Chen,Hudie Wei,Ming Guo,Shuyan Dai,Longying Jiang,Jun Li,Sitong Yue,Zhuchu Chen,Yongheng Chen
    PubMed 36697561
  • Molecules (Basel, Switzerland) 23:2018
    Discovery of a Natural Syk Inhibitor from Chinese Medicine through a Docking-Based Virtual Screening and Biological Assay Study.
    Applications:
    Unspecified application
    Reactive species:
    Unspecified reactive species
    Xing Wang et. al.
    PubMed 30487406

Key facts

Purity

>95%

Tags

Tag free

Applications

FuncS

Biologically active

Yes

Reactivity data

Application

FuncS

Reactivity

Reacts

Dilution info

-

Notes

-

Target data

Function

Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126). May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179).

Alternative names

Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF1, BRAF, RAFB1

Recommended products

  1. Loading...
  2. Loading...
  3. Loading...
  4. Loading...

Active Poly (Glu, Tyr) peptide is a Synthetic peptide. >95% purity and suitable for FuncS.

Alternative names

Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF1, BRAF, RAFB1

Key facts

Purity

>95%

Applications

FuncS

Biological activity

2300 nmol/min/mg Specific activity defined by radiometric assay, nmol of gamma-phosphate from ATP transferred to Unactive MEK1 and ERK1

Accession
P15056-1
Animal free

No

Species

Human

Concentration
Loading...
Storage buffer

pH: 7.5
Constituents: 0.394% Tris HCl

Sequence info

Amino acid sequence

Accession

P15056

Nature

Synthetic

Specifications

Form

Liquid

Additional notes

Purified by affinity chromatography

General info

Function

Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126). May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179).

Sequence similarities

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

Post-translational modifications

Phosphorylation at Ser-365 by SGK1 inhibits its activity.

Subcellular localisation

Nucleus

Storage

Shipped at conditions

Blue Ice

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

This product is an active protein and may elicit a biological response in vivo, handle with caution.

Notes

Ratio for molar concentration 4:1 Glu, Tyr (amount of each amino acid in the solution).

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

0 product images

    Downloads

    Product protocols

    For this product, it's our understanding that no specific protocols are required. You can:

    Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

    For licensing inquiries, please contact partnerships@abcam.com