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Active Poly (Glu, Tyr) peptide is a Synthetic peptide. >95% purity and suitable for FuncS.
Alternative names=Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF1, BRAF, RAFB1
- Purity
>95%
- Tags
Tag free
- Applications
FuncS
- Biologically active
Yes
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application FuncS | Reactivity Reacts | Dilution info - | Notes - |
Recommended products
Active Poly (Glu, Tyr) peptide is a Synthetic peptide. >95% purity and suitable for FuncS.
Alternative names=Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF1, BRAF, RAFB1
Key facts
- Purity
>95%
- Tags
Tag free
- Applications
FuncS
- Biologically active
Yes
- Biological activity
2300 nmol/min/mg Specific activity defined by radiometric assay, nmol of gamma-phosphate from ATP transferred to Unactive MEK1 and ERK1
- Accession
- P15056-1
- Animal free
No
- Nature
Synthetic
- Species
Human
- Concentration
- Storage buffer
pH: 7.5
Constituents: 0.394% Tris HCl
Specifications
- Form
Liquid
- Additional notes
Purified by affinity chromatography
General info
- Function
Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126). May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179).
- Sequence similarities
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
- Post-translational modifications
Phosphorylation at Ser-365 by SGK1 inhibits its activity.
- Subcellular localisation
Nucleus
Storage
- Shipped at conditions
Blue Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Avoid freeze / thaw cycle
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Notes
Ratio for molar concentration 4:1 Glu, Tyr (amount of each amino acid in the solution).
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