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AB176148

Angiotensin II Type 1 Receptor peptide

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(0 Publication)

Angiotensin II Type 1 Receptor peptide is a Synthetic blocking peptide.

View Alternative Names

AGTR1A, AGTR1B, AT2R1, AT2R1B, AGTR1, Type-1 angiotensin II receptor, AT1AR, AT1BR, Angiotensin II type-1 receptor, AT1 receptor

Key facts

Tags

Tag free

Applications

BL

applications

Biologically active

No

Accession

P30556

Animal free

No

Carrier free

No

Species

Human

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Complementary Products

Primary Antibodies

AB124734

Anti-Angiotensin II Type 1 Receptor antibody [EPR3873]

RabMAb|Recombinant

Indirect ELISA - Anti-Angiotensin II Type 1 Receptor antibody [EPR3873] (AB124734)

  • 2
  • 1
Proteins & Peptides

AB157870

Recombinant Human Angiotensin II Type 1 Receptor protein

SDS-PAGE - Recombinant Human Angiotensin II Type 1 Receptor protein (AB157870)

  • 0
  • 0
Biochemicals

AB141325

Angiotensin I (human, mouse, rat), Endogenous peptide hormone

Chemical Structure - Angiotensin I (human, mouse, rat), Endogenous peptide hormone (AB141325)

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  • 0
Primary Antibodies

AB76299

Anti-Erk1 (pT202/pY204) + Erk2 (pT185/pY187) antibody [EP197Y]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Western blot - Anti-Erk1 (pT202/pY204) + Erk2 (pT185/pY187) antibody [EP197Y] (AB76299)

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  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "BL": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"","proteinLength":null,"predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Synthetic","expressionSystem":null,"accessionNumber":"P30556","tags":[]}]
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Properties and storage information

False
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General info

Function

Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney (PubMed : 15611106, PubMed : 1567413, PubMed : 25913193, PubMed : 26420482, PubMed : 30639100, PubMed : 32079768, PubMed : 8987975). The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C (PubMed : 15611106).. (Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, it is able to recognize and internalize the complex formed by secreted ACE2 and SARS-CoV-2 spike protein through DNM2/dynamin 2-dependent endocytosis.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Post-translational modifications

C-terminal Ser or Thr residues may be phosphorylated.

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Product protocols

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Target data

Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney (PubMed : 15611106, PubMed : 1567413, PubMed : 25913193, PubMed : 26420482, PubMed : 30639100, PubMed : 32079768, PubMed : 8987975). The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C (PubMed : 15611106).. (Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, it is able to recognize and internalize the complex formed by secreted ACE2 and SARS-CoV-2 spike protein through DNM2/dynamin 2-dependent endocytosis.
See full target information AGTR1
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