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AB204865

Ezrin / Radixin / Moesin peptide

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Ezrin / Radixin / Moesin peptide is a Synthetic peptide. >97% and suitable for FuncS, HPLC.

View Alternative Names

VIL2, EZR, Ezrin, Cytovillin, Villin-2, p81

Key facts

Purity

>97% HPLC

Tags

Tag free

Applications

FuncS, HPLC

applications

Biologically active

No

Accession

P15311

Animal free

No

Carrier free

No

Species

Human

Reconstitution

reconstitute with 20 mM Tris-HCl, pH 7.5 at 1mg/mL

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

ab204865 (Ezrin / Radixin / Moesin peptide) can be utilized as a substrate for the active protein kinase ab177261 (Active human LRRK2 protein fragment)
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Sequence info

[{"sequence":"RLGRDKYKTLRQIRQ","proteinLength":null,"predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Synthetic","expressionSystem":null,"accessionNumber":null,"tags":[]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Lyophilized

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General info

Function

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Post-translational modifications

Phosphorylated by tyrosine-protein kinases. Phosphorylation by ROCK2 suppresses the head-to-tail association of the N-terminal and C-terminal halves resulting in an opened conformation which is capable of actin and membrane-binding (By similarity).. S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex.

Subcellular localisation

Cytoskeleton

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Product protocols

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Target data

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
See full target information EZR

Additional targets

Radixin,Moesin
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Complementary Products

Primary Antibodies

AB52495

Anti-Radixin/RDX antibody [EP1862Y]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-Radixin/RDX antibody [EP1862Y] (AB52495)

  • 5
  • 4
Proteins & Peptides

AB132942

Recombinant Human Ezrin protein

SDS-PAGE - Recombinant Human Ezrin protein (AB132942)

  • 0
  • 0
Primary Antibodies

AB40839

Anti-Ezrin antibody [EP886Y] - Plasma Membrane Marker

RabMAb|Recombinant|KO Validated|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-Ezrin antibody [EP886Y] - Plasma Membrane Marker (AB40839)

  • 5
  • 5
Primary Antibodies

AB52490

Anti-Moesin antibody [EP1863Y]

RabMAb|Recombinant|KO Validated

Flow Cytometry (Intracellular) - Anti-Moesin antibody [EP1863Y] (AB52490)

  • 5
  • 5

Product promise

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