Hsp27 peptide is a Synthetic peptide. >98% purity and suitable for FuncS, HPLC.
R R L N R Q L S V A - a m i d e
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application FuncS | Reactivity Reacts | Dilution info - | Notes - |
Application HPLC | Reactivity Reacts | Dilution info - | Notes - |
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Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).
HSP27, HSP28, HSPB1, Heat shock protein beta-1, HspB1, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, Heat shock protein family B member 1, Stress-responsive protein 27, HSP 27, SRP27
Hsp27 peptide is a Synthetic peptide. >98% purity and suitable for FuncS, HPLC.
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).
Belongs to the small heat shock protein (HSP20) family.
Phosphorylated upon exposure to protein kinase C activators and heat shock (PubMed:8325890). Phosphorylation by MAPKAPK2 and MAPKAPK3 in response to stress dissociates HSPB1 from large small heat-shock protein (sHsps) oligomers and impairs its chaperone activity and ability to protect against oxidative stress effectively. Phosphorylation by MAPKAPK5 in response to PKA stimulation induces F-actin rearrangement (PubMed:1332886, PubMed:19166925, PubMed:8093612).
ab204861 (Hsp27 peptide) can be utilized as a substrate for the following active protein kinases:
Recombinant human DCLK2 protein ab85758 (Active human DCAMKL2 protein fragment)
Recombinant human MK2 protein ab60307 (Active MAPKAP Kinase 2 protein fragment)
Recombinant human MK-3 protein ab60308 (Active human MAPKAP Kinase 3 full length protein)
Recombinant human PRAK/MK5 protein ab125743 (Active human PRAK full length protein)
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