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Human Kindlin-1 peptide is a Synthetic blocking peptide. >70% purity and suitable for BL.

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Key facts

Purity
>70% HPLC
Tags
Tag free
Applications
BL
Biologically active
No

Reactivity data

Application
BL
Reactivity
Reacts
Dilution info
-
Notes

-

Target data

Function

Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.

Alternative names

C20orf42, KIND1, URP1, FERMT1, Fermitin family homolog 1, Kindlerin, Kindlin syndrome protein, Kindlin-1, Unc-112-related protein 1

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Human Kindlin-1 peptide is a Synthetic blocking peptide. >70% purity and suitable for BL.

Key facts

Purity
>70% HPLC
Applications
BL
Accession
Q9BQL6-1
Animal free
No
Species
Human
Concentration
Loading...
Storage buffer

pH: 6.75
Constituents: 0.87% Sodium chloride, 0.714% HEPES, 0.0584% EDTA, 0.001% Sorbitan monolaurate, ethoxylated

Sequence info

Amino acid sequence

Accession
Q9BQL6
Nature
Synthetic

Specifications

Form
Liquid
Additional notes

70 - 90% by HPLC

General info

Function

Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.

Sequence similarities

Belongs to the kindlin family.

Subcellular localisation
Cytoskeleton

Storage

Shipped at conditions
Blue Ice
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn't dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

This product was previously labelled as Kindlin

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