Marburg-Musoke virus-like particles (MMARV VLP)
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Marburg-Musoke virus-like particles (MMARV VLP) is a Marburg virus - Musoke, Kenya, 1980 protein, expressed in Sf9 cells, with >75%, suitable for WB.
View Alternative Names
Matrix protein VP40, Marburg VP40, Membrane-associated protein VP40, mVP40
- WB
Supplier Data
Western blot - Marburg-Musoke virus-like particles (MMARV VLP) (AB326317)
Western Blot was used to confirm the presence of MMARV-specific GP, NP and VP40 in the VLP. VLP sample was heat-denatured under reducing condition and loaded at 1 µg.
(A) GP2 containing protein bands are visualized using 0.5 µg/mL of anti-MARV GP rabbit pAb. GP is highly glycosylated and most often detected at a molecular weight higher than the theoretical size due to the altered mobility.
(B) NP was detected as a prominent band at ~90 kDa and other NP-containing fragments, using 0.5 µg/mL of anti-MARV NP rabbit pAb.
(C) VP40 was detected as a prominent band at ~35 kDa and other VP40-containing fragments, using 0.5 µg/mL of anti-MARV VP40 rabbit pAb.
All lanes:
Western blot - Marburg-Musoke virus-like particles (MMARV VLP) (ab326317) at 1 µg
Observed band size: 35 kDa,90 kDa
false
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Plays an essential role virus particle assembly and budding (PubMed : 33673144). Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. The interaction with host E3 ubiquitin ligase SMURF2 facilitates virus budding (PubMed : 33673144). The interaction with the nucleocapsid and the plasma membrane may also facilitate virus budding. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur (By similarity). May play a role in genome replication (By similarity).
Sequence similarities
Belongs to the filoviridae matrix protein VP40 family.
Subcellular localisation
Host late endosome membrane
Target data
Product promise
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