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AB91203

Mouse C1QA peptide

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(1 Publication)

Mouse C1QA peptide is a Synthetic blocking peptide. >70% and suitable for BL.

View Alternative Names

Complement C1q subcomponent subunit A, C1qa

Key facts

Purity

>70% HPLC

Tags

Tag free

Applications

BL

applications

Biologically active

No

Accession

P98086

Animal free

No

Carrier free

No

Species

Mouse

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "BL": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn't dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
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Sequence info

[{"sequence":null,"proteinLength":null,"predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Synthetic","expressionSystem":null,"accessionNumber":"P98086","tags":[]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
-20°C
False
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Specifications

Form

Lyophilized

Additional notes

70 - 90% by HPLC

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General info

Function

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Post-translational modifications

O-linked glycans are Glc-Gal disaccharides typically found as secondary modifications of hydroxylated lysines in collagen-like domains.. Proline residues in the collagen-like domain motif, GXPG, are typically 4-hydroxylated.

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Product protocols

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Target data

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
See full target information C1qa
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 16:918 PubMed39843445

2025

Nonapoptotic caspase-3 guides C1q-dependent synaptic phagocytosis by microglia.

Applications

Unspecified application

Species

Unspecified reactive species

Megumi Andoh,Natsuki Shinoda,Yusuke Taira,Tasuku Araki,Yuka Kasahara,Haruki Takeuchi,Masayuki Miura,Yuji Ikegaya,Ryuta Koyama
View all publications
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Complementary Products

Primary Antibodies

AB182451

Anti-C1q antibody [4.8]

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Frozen sections) - Anti-C1q antibody [4.8] (AB182451)

  • 4
  • 6
Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

  • 5
  • 15
Primary Antibodies

AB306491

HRP Anti-C1QC antibody [EPR2984Y]

RabMAb|Recombinant

  • 0
  • 0
Assay Kits

AB291069

Mouse C1q ELISA Kit

  • 0
  • 1

Product promise

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