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Mouse Dnd1 peptide is a Synthetic blocking peptide. >90% purity and suitable for BL.

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Key facts

Purity
>90% HPLC
Tags
Tag free
Applications
BL
Biologically active
No

Reactivity data

Application
BL
Reactivity
Reacts
Dilution info
-
Notes

-

Target data

Function

RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity).

Alternative names

RBMS4, DND1, Dead end protein homolog 1

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Mouse Dnd1 peptide is a Synthetic blocking peptide. >90% purity and suitable for BL.

Key facts

Purity
>90% HPLC
Applications
BL
Accession
Q8IYX4-1
Animal free
No
Species
Human
Concentration
Loading...
Storage buffer

pH: 6.75
Constituents: 0.87% Sodium chloride, 0.714% HEPES, 0.0584% EDTA, 0.001% Sorbitan monolaurate, ethoxylated

Sequence info

Amino acid sequence

Accession
Q8IYX4
Nature
Synthetic

Specifications

Form
Liquid

General info

Function

RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity).

Subcellular localisation
Nucleus

Storage

Shipped at conditions
Blue Ice
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn't dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

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