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Mouse Glutamine Synthetase peptide is a Synthetic peptide. >70% purity.

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Purity

>70% HPLC

Tags

Tag free

Biologically active

No

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Target data

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Mouse Glutamine Synthetase peptide is a Synthetic peptide. >70% purity.

Key facts

Purity

>70% HPLC

Accession
P15105-1
Animal free

No

Nature

Synthetic

Species

Mouse

Concentration
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Storage buffer

pH: 6.75
Constituents: 0.87% Sodium chloride, 0.714% HEPES, 0.0584% EDTA, 0.001% Tween

Specifications

Form

Liquid

Additional notes

70 - 90% by HPLC

General info

Function

Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (PubMed:25870278). Essential for proliferation of fetal skin fibroblasts (By similarity). Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development (PubMed:30158707). Involved in angiogenesis by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation (By similarity). May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ (By similarity). Plays a role in ribosomal 40S subunit biogenesis (By similarity).

Sequence similarities

Belongs to the glutamine synthetase family.

Post-translational modifications

Palmitoylated; undergoes autopalmitoylation.

Subcellular localisation

Mitochondrion

Storage

Shipped at conditions

Blue Ice

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Product promise

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Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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