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Mouse Glutamine Synthetase peptide is a Synthetic peptide. >70% purity.
Alternative names=Glutamine synthetase, GS, Glutamate--ammonia ligase, Palmitoyltransferase GLUL, Glns, Glul
>70% HPLC
Tag free
No
Mouse Glutamine Synthetase peptide is a Synthetic peptide. >70% purity.
Alternative names=Glutamine synthetase, GS, Glutamate--ammonia ligase, Palmitoyltransferase GLUL, Glns, Glul
>70% HPLC
Tag free
No
No
Synthetic
Mouse
pH: 6.75
Constituents: 0.87% Sodium chloride, 0.714% HEPES, 0.0584% EDTA, 0.001% Tween
Liquid
70 - 90% by HPLC
Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (PubMed:25870278). Essential for proliferation of fetal skin fibroblasts (By similarity). Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development (PubMed:30158707). Involved in angiogenesis by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation (By similarity). May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ (By similarity). Plays a role in ribosomal 40S subunit biogenesis (By similarity).
Belongs to the glutamine synthetase family.
Palmitoylated; undergoes autopalmitoylation.
Mitochondrion
Blue Ice
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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