Native Cow Bovine Serum Albumin protein is a Cow Full Length protein, in the 25 to 607 aa range, expressed in Native, with >96% purity and suitable for WB, IHC.
>96% SDS-PAGE
Native
Tag free
WB, IHC
No
D T H K S E I A H R F K D L G E E H F K G L V L I A F S Q Y L Q Q C P F D E H V K L V N E L T E F A K T C V A D E S H A G C E K S L H T L F G D E L C K V A S L R E T Y G D M A D C C E K Q E P E R N E C F L S H K D D S P D L P K L K P D P N T L C D E F K A D E K K F W G K Y L Y E I A R R H P Y F Y A P E L L Y Y A N K Y N G V F Q E C C Q A E D K G A C L L P K I E T M R E K V L A S S A R Q R L R C A S I Q K F G E R A L K A W S V A R L S Q K F P K A E F V E V T K L V T D L T K V H K E C C H G D L L E C A D D R A D L A K Y I C D N Q D T I S S K L K E C C D K P L L E K S H C I A E V E K D A I P E N L P P L T A D F A E D K D V C K N Y Q E A K D A F L G S F L Y E Y S R R H P E Y A V S V L L R L A K E Y E A T L E E C C A K D D P H A C Y S T V F D K L K H L V D E P Q N L I K Q N C D Q F E K L G E Y G F Q N A L I V R Y T R K V P Q V S T P T L V E V S R S L G K V G T R C C T K P E S E R M P C T E D Y L S L I L N R L C V L H E K T P V S E K V T K C C T E S L V N R R P C F S A L T P D E T Y V P K A F D E K L F T F H A D I C T L P D T E K Q I K K Q T A L V E L L K H K P K A T E E Q L K T V M E N F V A F V D K C C A A D D K E A C F A V E G P K L V V S T Q T A L A
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Application IHC | Reactivity Reacts | Dilution info - | Notes - |
Select an associated product type
Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (PubMed:22677715). The shared binding site between zinc and calcium at residue Asp-272 suggests a crosstalk between zinc and calcium transport in the blood (Probable). The rank order of affinity is zinc > calcium > magnesium (Probable). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017).
Albumin, BSA, ALB
Native Cow Bovine Serum Albumin protein is a Cow Full Length protein, in the 25 to 607 aa range, expressed in Native, with >96% purity and suitable for WB, IHC.
>96% SDS-PAGE
Native
Tag free
WB, IHC
No
No
Cow
Reconstitute using deionized water.
D T H K S E I A H R F K D L G E E H F K G L V L I A F S Q Y L Q Q C P F D E H V K L V N E L T E F A K T C V A D E S H A G C E K S L H T L F G D E L C K V A S L R E T Y G D M A D C C E K Q E P E R N E C F L S H K D D S P D L P K L K P D P N T L C D E F K A D E K K F W G K Y L Y E I A R R H P Y F Y A P E L L Y Y A N K Y N G V F Q E C C Q A E D K G A C L L P K I E T M R E K V L A S S A R Q R L R C A S I Q K F G E R A L K A W S V A R L S Q K F P K A E F V E V T K L V T D L T K V H K E C C H G D L L E C A D D R A D L A K Y I C D N Q D T I S S K L K E C C D K P L L E K S H C I A E V E K D A I P E N L P P L T A D F A E D K D V C K N Y Q E A K D A F L G S F L Y E Y S R R H P E Y A V S V L L R L A K E Y E A T L E E C C A K D D P H A C Y S T V F D K L K H L V D E P Q N L I K Q N C D Q F E K L G E Y G F Q N A L I V R Y T R K V P Q V S T P T L V E V S R S L G K V G T R C C T K P E S E R M P C T E D Y L S L I L N R L C V L H E K T P V S E K V T K C C T E S L V N R R P C F S A L T P D E T Y V P K A F D E K L F T F H A D I C T L P D T E K Q I K K Q T A L V E L L K H K P K A T E E Q L K T V M E N F V A F V D K C C A A D D K E A C F A V E G P K L V V S T Q T A L A
Full Length
25 to 607
Native
Lyophilized
Proprietary heat-shock process.
Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (PubMed:22677715). The shared binding site between zinc and calcium at residue Asp-272 suggests a crosstalk between zinc and calcium transport in the blood (Probable). The rank order of affinity is zinc > calcium > magnesium (Probable). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017).
Belongs to the ALB/AFP/VDB family.
Phosphorylated by FAM20C in the extracellular medium.
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
The product is suitable to use in blocking experiments. This product contains:-
Moisture: 1.4%
Ash: 1.4%
Heavy Metals: <0.44ppm
Bovine IgG: Not detected
Protein: 100% (Biuret)
Albumin: 100% (electrophoresis)
This supplementary information is collated from multiple sources and compiled automatically.
Bovine serum albumin (BSA) also known as albumin bovine serum boasts a molecular weight of approximately 66.5 kDa. This protein is found in the blood serum of cows and is derived from plasma. BSA or bovine albumin acts as a transport protein that binds to various substances including fatty acids and hormones facilitating their movement through the blood. In the lab scientists often use the BSA protein as a standard or blocking agent in experiments particularly in ELISA and Western blot assays.
Proteins such as BSA play a critical role in maintaining osmotic pressure and pH balance in biological fluids. BSA does not form part of a larger protein complex but interacts with numerous small molecules and ions stabilizing their concentrations in the bloodstream. The interaction of albumin bovine serum with fatty acids is especially important for modulating the bioavailability of lipophilic molecules.
Albumin actively contributes to lipid metabolism and transport pathways. It interacts closely with other proteins involved in these processes such as lipoproteins. BSA's binding affinity for various drugs and toxins also places it within the detoxification and excretory pathways ensuring the stability and solubility of these substances in circulation.
Scientists have studied BSA for its relevance to liver and kidney diseases given its role in carrying molecules and maintaining osmotic balance. Reduced levels of bovine albumin may indicate liver dysfunction or nephrotic syndrome where protein loss through urine is a concern. BSA's interaction with proteins such as globulin is also significant when investigating these conditions as the balance between these proteins can reflect the body's overall protein status.
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