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Native Dog Canine Albumin protein is a Dog Full Length protein, in the 25 to 608 aa range, expressed in Native, with >95% purity and suitable for SDS-PAGE.

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Publications

Key facts

Purity

>95% SDS-PAGE

Expression system

Native

Tags

Tag free

Applications

SDS-PAGE

Biologically active

No

Reactivity data

Application

SDS-PAGE

Reactivity

Reacts

Dilution info

-

Notes

-

Target data

Function

Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (By similarity). Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity).

Alternative names

Recommended products

Native Dog Canine Albumin protein is a Dog Full Length protein, in the 25 to 608 aa range, expressed in Native, with >95% purity and suitable for SDS-PAGE.

Alternative names

Key facts

Purity

>95% SDS-PAGE

Expression system

Native

Applications

SDS-PAGE

Accession
P49822-1
Animal free

No

Species

Dog

Reconstitution

Add deionized water or buffer to original or desired volume. The volume was 10 ml before lyophilization.

Concentration
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Sequence info

Amino acid sequence

Accession

P49822

Protein length

Full Length

Predicted molecular weight

68.6 kDa

Amino acids

25 to 608

Nature

Native

Specifications

Form

Lyophilized

Additional notes

purified by proprietary fractionation methods

General info

Function

Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (By similarity). Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity).

Sequence similarities

Belongs to the ALB/AFP/VDB family.

Post-translational modifications

Phosphorylated by FAM20C in the extracellular medium.

Storage

Shipped at conditions

Blue Ice

Appropriate long-term storage conditions

-80°C

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