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AB285482

Native Human Ceruloplasmin protein

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Native Human Ceruloplasmin protein is a Human Full Length protein, expressed in Mammalian, with >95%, suitable for SDS-PAGE.

View Alternative Names

Ceruloplasmin, Cuproxidase ceruloplasmin, Ferroxidase ceruloplasmin, Glutathione peroxidase ceruloplasmin, Glutathione-dependent peroxiredoxin ceruloplasmin, CP

1 Images
SDS-PAGE - Native Human Ceruloplasmin protein (AB285482)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Native Human Ceruloplasmin protein (AB285482)

1. Ceruloplasmin - 5 μg (reduced / heated)

2. Ceruloplasmin - 10 μg (reduced / heated)

3. Ceruloplasmin - 20 μg (reduced / heated)

4. LMW Standard

5. Ceruloplasmin - 5 μg (non-reduced / no heat)

6. Ceruloplasmin - 10 μg (non-reduced / no heat)

7. Ceruloplasmin - 20 μg (non-reduced / no heat)

Key facts

Purity

>95% SDS-PAGE

Expression system

Mammalian

Tags

Tag free

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P00450

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in water

Storage buffer

pH: 6.8 Constituents: 1.06% Tripotassium orthophosphate, 0.75% Potassium chloride, 0.26% Aminocaproic acid, 0.15% EDTA

storage-buffer

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Reagents, Controls & Accessories

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SDS-PAGE - Prestained Protein Ladder - Broad molecular weight (11-250 kDa, 5-color, 12 bands) (AB325996)

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Assay Kits

AB189579

Human alpha 1 Antitrypsin ELISA Kit (SERPINA1)

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ELISA - Human alpha 1 Antitrypsin ELISA Kit (SERPINA1) (AB189579)

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Assay Kits

AB215541

Human Lipocalin-2 ELISA Kit

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AB181423

Human Beta-2-Microglobulin ELISA Kit

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ELISA - Human Beta-2-Microglobulin ELISA Kit (AB181423)

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Primary Antibodies

AB118820

Anti-Factor H antibody [OX-24]

Trial Size

ELISA - Anti-Factor H antibody [OX-24] (AB118820)

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 4096 Ceruloplasmin, Human Plasma. 4096-1000 is the same size as the 1 mg size of ab285482.
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Sequence info

[{"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"132 kDa","actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Native","expressionSystem":null,"accessionNumber":"P00450","tags":[]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate long-term storage conditions
-20°C
False
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Specifications

Form

Lyophilized

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General info

Function

Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane (PubMed : 16150804). Copper ions provide a large number of enzymatic activites. Oxidizes highly toxic ferrous ions to the ferric state for further incorporation onto apo-transferrins, catalyzes Cu(+) oxidation and promotes the oxidation of biogenic amines such as norepinephrin and serotonin (PubMed : 14623105, PubMed : 4643313, PubMed : 5912351). Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1 (By similarity). Has glutathione peroxidase-like activity, can remove both hydrogen peroxide and lipid hydroperoxide in the presence of thiols (PubMed : 10481051). Also shows NO-oxidase and NO2 synthase activities that determine endocrine NO homeostasis (PubMed : 16906150).

Sequence similarities

Belongs to the multicopper oxidase family.

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Product protocols

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Target data

Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane (PubMed : 16150804). Copper ions provide a large number of enzymatic activites. Oxidizes highly toxic ferrous ions to the ferric state for further incorporation onto apo-transferrins, catalyzes Cu(+) oxidation and promotes the oxidation of biogenic amines such as norepinephrin and serotonin (PubMed : 14623105, PubMed : 4643313, PubMed : 5912351). Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1 (By similarity). Has glutathione peroxidase-like activity, can remove both hydrogen peroxide and lipid hydroperoxide in the presence of thiols (PubMed : 10481051). Also shows NO-oxidase and NO2 synthase activities that determine endocrine NO homeostasis (PubMed : 16906150).
See full target information CP
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Product promise

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