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AB90285

Native Human IgG FC fragment protein

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(16 Publications)

Native Human IgG FC fragment protein is a Full Length protein with >95% purity and suitable for SDS-PAGE. The predicted molecular weight of ab90285 native protein is 50 kDa.

- Save time and ensure accurate results - use our IgG Fc fragment protein as a control
- Cited in over 10 publications
1 Images
SDS-PAGE - Native Human IgG FC fragment protein (AB90285)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Native Human IgG FC fragment protein (AB90285)

4-12% Bis-Tris NuPAGE Gel analysis of ab90285.

Lanes 1-3 show 5, 10 and 15 μg, respectively; run under heated/reducing conditions.

Lanes 4-6 show 5, 10 and 15 μg, respectively; not heated/non-reducing conditions.

Key facts

Purity

>95% SDS-PAGE

Expression system

Native

Tags

Tag free

Applications

SDS-PAGE

applications

Biologically active

No

Animal free

No

Carrier free

No

Storage buffer

pH: 8 Preservative: 0.05% Sodium azide Constituents: 1.16% Sodium chloride, 0.79% Tris HCl

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>MW is 31kDa</p>" } } }
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Product details

The Native Human IgG FC fragment protein ab90285 is prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Ensure the validity of your result using our native human Immunoglobulin G (IgG) FC fragment protein as a control in SDS-PAGE.

The IgG Fc fragment does not bind antigen; however, it does contain the classic antigenic determinants and biological activity with respect to cytotrophic reactions, binding of complement and catabolic rate control.

Check out our protein gel staining guide for SDS-PAGE here

Protein Determination: Extinction Coefficient (ε) 0.1% at 280 nm, 1 cm pathway = 1.35

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Sequence info

[{"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"50 kDa","actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Native","expressionSystem":null,"accessionNumber":null,"tags":[]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Human IgG FC fragment
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Publications (16)

Recent publications for all applications. Explore the full list and refine your search

eLife 13: PubMed39401071

2024

Delivery of a Jagged1-PEG-MAL hydrogel with pediatric human bone cells regenerates critically sized craniofacial bone defects.

Applications

Unspecified application

Species

Unspecified reactive species

Archana Kamalakar,Brendan Tobin,Sundus Kaimari,M Hope Robinson,Afra I Toma,Timothy Cha,Samir Chihab,Irica Moriarity,Surabhi Gautam,Pallavi Bhattaram,Shelly Abramowicz,Hicham Drissi,Andres Garcia,Levi Wood,Steven L Goudy

Cell death & disease 15:128 PubMed38341429

2024

PRL-mediated STAT5B/ARRB2 pathway promotes the progression of prostate cancer through the activation of MAPK signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Tao Yang,Yongnan Chi,Xin'an Wang,Chengdang Xu,Xi Chen,Ying Liu,Shengsong Huang,Xuyou Zhu,Haoyang Zhang,Hui Zhuo,Denglong Wu

Cerebral cortex (New York, N.Y. : 1991) 33:10634-10648 PubMed37642601

2023

Ankyrin B promotes developmental spine regulation in the mouse prefrontal cortex.

Applications

Unspecified application

Species

Unspecified reactive species

Kelsey E Murphy,Bryce Duncan,Justin E Sperringer,Erin Zhang,Victoria Haberman,Elliott V Wyatt,Patricia Maness

Experimental and therapeutic medicine 26:439 PubMed37614427

2023

HOXC13 promotes cell proliferation, metastasis and glycolysis in breast cancer by regulating DNMT3A.

Applications

Unspecified application

Species

Unspecified reactive species

Hongrui Li,Pengcheng Gao,Haifeng Chen,Junjie Zhao,Xiangzhong Zhang,Ganggang Li,Liting Wang,Long Qin

Experimental and therapeutic medicine 24:551 PubMed35978937

2022

FOSL1 knockdown ameliorates DSS-induced inflammation and barrier damage in ulcerative colitis via MMP13 downregulation.

Applications

Unspecified application

Species

Unspecified reactive species

Lizhuan Ma,Xiujing Zhang,Chao Zhang,Bingxu Hou,Hongtao Zhao

Experimental and therapeutic medicine 22:1388 PubMed34650636

2021

Upregulation of AQP2 mediated by transcription factor FOXO1 inhibits TGF-β-induced fibrosis in human urothelial cells.

Applications

Unspecified application

Species

Unspecified reactive species

Yue Qiu,Zhaoquan Xing,Zhaoxin Guo,Zhaoxu Liu

Cancers 13: PubMed34298682

2021

A Conjugation Strategy to Modulate Antigen Binding and FcRn Interaction Leads to Improved Tumor Targeting and Radioimmunotherapy Efficacy with an Antibody Targeting Prostate-Specific Antigen.

Applications

Unspecified application

Species

Unspecified reactive species

Oskar Vilhelmsson Timmermand,Anders Örbom,Mohamed Altai,Wahed Zedan,Bo Holmqvist,Marcella Safi,Thuy A Tran,Sven-Erik Strand,Joanna Strand

Bone 143:115657 PubMed32980561

2020

JAGGED1 stimulates cranial neural crest cell osteoblast commitment pathways and bone regeneration independent of canonical NOTCH signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Archana Kamalakar,Jay M McKinney,Daniel Salinas Duron,Angelica M Amanso,Samir A Ballestas,Hicham Drissi,Nick J Willett,Pallavi Bhattaram,Andrés J García,Levi B Wood,Steven L Goudy

Clinical cancer research : an official journal of the American Association for Cancer Research 26:669-678 PubMed31672772

2019

EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid Leukemia.

Applications

Unspecified application

Species

Unspecified reactive species

Marius Bill,Aparna Pathmanathan,Malith Karunasiri,Changxian Shen,Matthew H Burke,Parvathi Ranganathan,Dimitrios Papaioannou,Nina C Zitzer,Katiri Snyder,Allison LaRocco,Allison E Walker,Zachary J Brannan,Ansel P Nalin,Aharon G Freud,Mikhail M Dikov,Xiaoli Zhang,Clara D Bloomfield,Ramiro Garzon,Adrienne M Dorrance

Cell death & disease 10:732 PubMed31570696

2019

MAG induces apoptosis in cerebellar granule neurons through p75 demarcating granule layer/white matter boundary.

Applications

Unspecified application

Species

Unspecified reactive species

Diana Fernández-Suárez,Favio A Krapacher,Annika Andersson,Carlos F Ibáñez,Lilian Kisiswa
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com