Native Human Von Willebrand Factor protein
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(3 Publications)
Native Human Von Willebrand Factor protein is a Human Full Length protein with >95% purity and suitable for SDS-PAGE. The predicted molecular weight of ab88533 native protein is 260 kDa (monomer).
- Save time and ensure accurate results- use our Von Willebrand Factor (VWF) protein as a control.
View Alternative Names
F8VWF, VWF, von Willebrand factor, vWF
- SDS-PAGE
Supplier Data
SDS-PAGE - Native Human Von Willebrand Factor protein (AB88533)
SDS-PAGE analysis of ab88533 for 1ug protein.
Novex 4-12% Bis-Tris Gel
NR= non-reduced; R = reduced
Reactivity data
Product details
Ensure the validity of your result using our native human VWF protein ab88533 as a positive control in SDS-PAGE.
Required thawing procedure:
- Remove the vial from frozen storage and place it into a 37°C water bath
- Leave the vial in the water bath undisturbed for two minutes after the disappearance of the last of the frozen material
- Remove the vial from the water bath and mix by gentle agitation or gentle mixing with a pipette.
If a precipitate is observed, continue to warm the vial in the 37°C water bath for an additional 2 to 3 minutes and mix again
Check out our protein gel staining guide for SDS-PAGE here
The VWF protein ab88533 is prepared from plasma shown to be non reactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II.
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
The protein expressed by the gene VWF is important for maintaining hemostasis. It promotes platelet adhesion at sites of vascular injury by forming a molecular bridge between the sub-endothelial collagen matrix and the platelet-surface receptor complex GPIb-IX-V. Additionally, it acts as a chaperone for coagulation factor VIII, delivering it to the injury site, stabilizing its heterodimeric structure, and protecting it from premature clearance from plasma. This supplementary information is collated from multiple sources and compiled automatically.
Post-translational modifications
All cysteine residues are involved in intrachain or interchain disulfide bonds.. N- and O-glycosylated.
Target data
Publications (3)
Recent publications for all applications. Explore the full list and refine your search
Frontiers in cellular and infection microbiology 11:694957 PubMed34095003
2021
Applications
Unspecified application
Species
Unspecified reactive species
Journal of thrombosis and haemostasis : JTH 18:942-954 PubMed31894636
2020
Applications
Unspecified application
Species
Unspecified reactive species
Nature chemical biology 16:423-429 PubMed31907373
2020
Applications
Unspecified application
Species
Unspecified reactive species
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Product promise
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