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Native Human Von Willebrand Factor protein is a Human Full Length protein, expressed in Native, with >95% purity and suitable for SDS-PAGE.

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Key facts

Purity

>95% SDS-PAGE

Expression system

Native

Tags

Tag free

Applications

SDS-PAGE

Biologically active

No

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Reactivity data

Application

SDS-PAGE

Reactivity

Reacts

Dilution info

-

Notes

-

Target data

Function

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

Alternative names

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Native Human Von Willebrand Factor protein is a Human Full Length protein, expressed in Native, with >95% purity and suitable for SDS-PAGE.

Alternative names

Key facts

Purity

>95% SDS-PAGE

Expression system

Native

Applications

SDS-PAGE

Accession
P04275-1
Animal free

No

Species

Human

Concentration
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Storage buffer

pH: 6.8
Constituents: 0.75% Glycine, 0.735% Sodium citrate, 0.58% Sodium chloride

Sequence info

Amino acid sequence

Accession

P04275

Protein length

Full Length

Nature

Native

Specifications

Form

Liquid

General info

Function

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

Post-translational modifications

All cysteine residues are involved in intrachain or interchain disulfide bonds.

Storage

Shipped at conditions

Dry Ice

Appropriate long-term storage conditions

-80°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Required thawing procedure: Remove the vial from frozen storage and place it into a 37°C water bath. Leave the vial in the water bath undisturbed for two minutes after the disappearance of the last of the frozen material. Remove the vial from the water bath and mix by gentle agitation or gentle mixing with a pipette. If a precipitate is observed, continue to warm the vial in the 37°C water bath for an additional 2 to 3 minutes and mix again.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • SDS-PAGE - Native Human Von Willebrand Factor protein (ab88533), expandable thumbnail

    SDS-PAGE - Native Human Von Willebrand Factor protein (ab88533)

    SDS-PAGE analysis of ab88533 for 1ug protein.
    Novex 4-12% Bis-Tris Gel
    NR= non-reduced; R = reduced

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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