Native Staphylococcus aureus Protein A (HRP) is a Full Length S. aureus Protein A (Spa) protein conjugated to Horseradish Peroxidase (HRP) with >95% purity and suitable for western blot, ELISA, IHC, Dot blot and more.The predicted molecular weight of ab7456 protein is 56 kDa.
- Save time and ensure accurate results - use our S. aureus Protein A (HRP) to probe and detect IgG
- Cited in over 15 publications
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application Dot | Reactivity Reacts | Dilution info - | Notes - |
Application IM | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info 1/10000 - 1/40000 | Notes - |
Application ELISA | Reactivity Reacts | Dilution info 1/20000 - 1/200000 | Notes - |
Application IHC-P | Reactivity Reacts | Dilution info 1/1000 - 1/5000 | Notes - |
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Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins (By similarity). In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin. Acts directly as a pro-inflammatory factor in the lung through its ability to bind and activate tumor necrosis factor alpha receptor 1/TNFRSF1A (By similarity).
Protein A
Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SpA, spa
Native Staphylococcus aureus Protein A (HRP) is a Full Length S. aureus Protein A (Spa) protein conjugated to Horseradish Peroxidase (HRP) with >95% purity and suitable for western blot, ELISA, IHC, Dot blot and more.The predicted molecular weight of ab7456 protein is 56 kDa.
- Save time and ensure accurate results - use our S. aureus Protein A (HRP) to probe and detect IgG
- Cited in over 15 publications
Preservative: 0.01% Gentamicin sulphate
Constituents: 1% BSA, 0.88% Sodium chloride, 0.424% Potassium phosphate solution
Protein A Peroxidase Conjugation was prepared from chromatographically pure Protein A.
Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins (By similarity). In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin. Acts directly as a pro-inflammatory factor in the lung through its ability to bind and activate tumor necrosis factor alpha receptor 1/TNFRSF1A (By similarity).
Belongs to the immunoglobulin-binding protein SpA family.
Molecular Weight (protein A): 42,000 daltons
Extinction Coefficient: 0.1% at 280 nm is 0.14 (E0.1% of 0.14)
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