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AB236276

Recombinant Cytomegalovirus Envelope glycoprotein B (Tagged)

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Recombinant Cytomegalovirus Envelope glycoprotein B (Tagged) is a Rhesus cytomegalovirus strain 68-1 Fragment protein, in the 745 to 854 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

View Alternative Names

Envelope glycoprotein B, gB, UL55

1 Images
SDS-PAGE - Recombinant Cytomegalovirus Envelope glycoprotein B (Tagged) (AB236276)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Cytomegalovirus Envelope glycoprotein B (Tagged) (AB236276)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis with 5% enrichment gel and 15% separation gel of ab236276.

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P89053

Animal free

No

Carrier free

No

Species

Rhesus cytomegalovirus strain 68-1

Storage buffer

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MRQKRAYEKPFEHFFPYVVPPTTVKEAPPSYEQSQYENIKEKAASATKEFSLEEAYQMLLALQKLDQEKRRKAEADDEDFASNGQSAGFLDRLRNRRRGGYQKIQNEYEV","proteinLength":"Fragment","predictedMolecularWeight":"18 kDa","actualMolecularWeight":null,"aminoAcidEnd":854,"aminoAcidStart":745,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P89053","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.

Sequence similarities

Belongs to the herpesviridae glycoprotein B family.

Post-translational modifications

A proteolytic cleavage by host furin generates two subunits that remain linked by disulfide bonds.

Subcellular localisation

Host endosome membrane

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Product protocols

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Target data

Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
See full target information Envelope glycoprotein B

Additional targets

Cytomegalovirus Envelope glycoprotein B
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