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AB256435

Recombinant Cytomegalovirus Glycoprotein B (Fc Chimera)

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Recombinant Cytomegalovirus Glycoprotein B (Fc Chimera) is a Human herpesvirus 5 strain Towne Fragment protein, in the 1 to 700 aa range, expressed in HEK 293 cells, with >95%, suitable for SDS-PAGE.

View Alternative Names

UL55, gB, Envelope glycoprotein B, CMV glycoprotein B, Glycoprotein B, HCMV, HHV5 glycoprotein B, UL55

2 Images
ELISA - Recombinant Cytomegalovirus Glycoprotein B (Fc Chimera) (AB256435)
  • ELISA

Supplier Data

ELISA - Recombinant Cytomegalovirus Glycoprotein B (Fc Chimera) (AB256435)

Assay of purified ab256435, detected by a Mouse anti-CMV gB antibody. Antigen coated onto plate at 1ug/ml, with antibody titrated from 20ug/ml as indicated.

SDS-PAGE - Recombinant Cytomegalovirus Glycoprotein B (Fc Chimera) (AB256435)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Cytomegalovirus Glycoprotein B (Fc Chimera) (AB256435)

Reducing SDS-PAGE analysis of purified ab256435 running at approximately 140-160kda.

Key facts

Purity

>95% SDS-PAGE

Expression system

HEK 293 cells

Tags

Fc tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P13201

Animal free

No

Carrier free

No

Species

Human herpesvirus 5 strain Towne

Storage buffer

pH: 7 - 8 Constituents: PBS

storage-buffer

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Complementary Products

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AB43046

Recombinant HSV2 gD protein

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Proteins & Peptides

AB43042

Recombinant Cytomegalovirus UL80a protein

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Primary Antibodies

AB6506

Anti-HSV1 + HSV2 gB antibody [10B7]

Immunocytochemistry/ Immunofluorescence - Anti-HSV1 + HSV2 gB antibody [10B7] (AB6506)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"linker":null,"sequence":"Strain: Human betaherpesvirus 5 towne strain.","proteinLength":"Fragment","predictedMolecularWeight":"102 kDa","actualMolecularWeight":null,"aminoAcidEnd":700,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"P13201","tags":[{"tag":"Fc","terminus":"C-Terminus"}]}]
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Properties and storage information

Form
Liquid
Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Storage information
Avoid freeze / thaw cycle
False
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General info

Function

Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.

Sequence similarities

Belongs to the herpesviridae glycoprotein B family.

Post-translational modifications

A proteolytic cleavage by host furin generates two subunits that remain linked by disulfide bonds.

Subcellular localisation

Host endosome membrane

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Product protocols

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Target data

Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
See full target information gB
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Product promise

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