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AB256436

Recombinant Cytomegalovirus Glycoprotein B (Fc Chimera)

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Recombinant Cytomegalovirus Glycoprotein B (Fc Chimera) is a Human herpesvirus 5 strain AD169 Fragment protein, in the 1 to 700 aa range, expressed in HEK 293 cells, with >95%, suitable for SDS-PAGE.

View Alternative Names

UL55, gB, Envelope glycoprotein B, CMV glycoprotein B, Glycoprotein B, HCMV, HHV5 glycoprotein B, UL55

1 Images
SDS-PAGE - Recombinant Cytomegalovirus Glycoprotein B (Fc Chimera) (AB256436)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Cytomegalovirus Glycoprotein B (Fc Chimera) (AB256436)

Reducing SDS-PAGE analysis of ab256436 running at an expected MW of 140-160kDa.

Lane 1 : 2.7 μg ab256436.

Lane 2 : 0.67 μg ab256436.

Lane 3 : 0.3 μg ab256436.

Key facts

Purity

>95% SDS-PAGE

Expression system

HEK 293 cells

Tags

Fc tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P06473

Animal free

No

Carrier free

No

Species

Human herpesvirus 5 strain AD169

Storage buffer

pH: 7 - 8 Constituents: PBS

storage-buffer

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Complementary Products

Proteins & Peptides

AB43046

Recombinant HSV2 gD protein

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Proteins & Peptides

AB43042

Recombinant Cytomegalovirus UL80a protein

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Primary Antibodies

AB6506

Anti-HSV1 + HSV2 gB antibody [10B7]

Immunocytochemistry/ Immunofluorescence - Anti-HSV1 + HSV2 gB antibody [10B7] (AB6506)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"linker":"10 amino acid glycine-serine linker","sequence":"","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":700,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"P06473","tags":[{"tag":"Fc","terminus":"C-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-80°C
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.

Sequence similarities

Belongs to the herpesviridae glycoprotein B family.

Post-translational modifications

A proteolytic cleavage by host furin generates two subunits that remain linked by disulfide bonds.

Subcellular localisation

Host endosome membrane

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Product protocols

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Target data

Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
See full target information gB
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Product promise

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