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Recombinant Cytomegalovirus pp65 protein is a Human herpesvirus 5 strain AD169 Full Length protein, expressed in Escherichia coli, with >95% purity and suitable for ELISA, WB.

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Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

ELISA, WB

Biologically active

No

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Reactivity data

Application

ELISA

Reactivity

Reacts

Dilution info

-

Notes

-

Application

WB

Reactivity

Reacts

Dilution info

-

Notes

-

Target data

Function

Counteracts the host antiviral immune response when activated and phosphorylated, by preventing IRF3 from entering the nucleus. Also participates in the transactivation of viral major immediate-early genes by the recruitment of host IFI16 to the promoters pf these genes.

Alternative names

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Recombinant Cytomegalovirus pp65 protein is a Human herpesvirus 5 strain AD169 Full Length protein, expressed in Escherichia coli, with >95% purity and suitable for ELISA, WB.

Alternative names

Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Applications

ELISA, WB

Accession
P06725-1
Animal free

No

Species

Human herpesvirus 5 strain AD169

Concentration
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Storage buffer

pH: 8
Constituents: 48.048% Urea, 0.394% Tris HCl, 0.039% 2-Mercaptoethanol

Sequence info

Amino acid sequence

Accession

Protein length

Full Length

Predicted molecular weight

62.9 kDa

Nature

Recombinant

Tags

His tag N-Terminus

Specifications

Form

Liquid

Additional notes

Sepharose derived purification.

General info

Function

Counteracts the host antiviral immune response when activated and phosphorylated, by preventing IRF3 from entering the nucleus. Also participates in the transactivation of viral major immediate-early genes by the recruitment of host IFI16 to the promoters pf these genes.

Sequence similarities

Belongs to the herpesviridae pp65 family.

Post-translational modifications

Phosphorylation may play a role in the localization of the protein.

Subcellular localisation

Host nucleus

Storage

Shipped at conditions

Blue Ice

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Specificity: Immunoreactive with sera of CMV-infected individuals.

Product promise

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In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
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