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AB233682

Recombinant dog IL-4 protein (Active)

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Recombinant dog IL-4 protein (Active) is a Dog Full Length protein, in the 25 to 132 aa range, expressed in Escherichia coli, with >95%, <1 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS.

View Alternative Names

Interleukin-4, IL-4, B-cell stimulatory factor 1, Lymphocyte stimulatory factor 1, BSF-1, IL4

2 Images
Functional Studies - Recombinant dog IL-4 protein (Active) (AB233682)
  • FuncS

Supplier Data

Functional Studies - Recombinant dog IL-4 protein (Active) (AB233682)

TF-1 cell proliferation : ED50 ≤ 25 ng/mL (≥ 4.0 x 104 units/mg).

SDS-PAGE - Recombinant dog IL-4 protein (Active) (AB233682)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant dog IL-4 protein (Active) (AB233682)

SDS-PAGE - Recombinant dog IL4 protein (Active) (ab233682) at 1 μg.

Lane 1 : Non-reducing conditions.

Lane 2 : Reducing conditions.

4-20% Tris-Glycine gel stained with Coomassie Blue.

Expected MW 12.9 kDa.

Key facts

Purity

>95% SDS-PAGE

Endotoxin level

<1 EU/µg

Expression system

Escherichia coli

Tags

Tag free

Applications

SDS-PAGE, FuncS

applications

Biologically active

Yes

Biological activity

TF-1 cell proliferation: ED50 ≤ 25 ng/mL (≥ 4.0 x 104 units/mg).

Accession

O77762

Animal free

No

Carrier free

No

Species

Dog

Reconstitution

Reconstitute at 0.1 mg/mL in water

Storage buffer

Constituents: 0.1% Trifluoroacetic acid

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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We recommend this product because it’s often used in the same experiment or related research.

We advise that you always check the datasheet to ensure it fits your experiments, or contact ourtechnical teamfor help.

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Product details

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Sequence info

[{"sequence":"MHNFNITIKEIIKMLNILTARNDSCMELTVKDVFTAPKNTSDKEIFCRAATVLRQIYTHNCSNRYLRGLYRNLSSMANKTCSMNEIKKSTLKDFLERLKVIMQKKYYRH","proteinLength":"Full Length","predictedMolecularWeight":"12.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":132,"aminoAcidStart":25,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"O77762","tags":[]}]
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
True
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Specifications

Form

Lyophilized

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General info

Function

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

Sequence similarities

Belongs to the IL-4/IL-13 family.

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Product protocols

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Target data

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
See full target information IL4
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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Alternative Version
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