Recombinant E. coli Acetate Kinase protein (His tag)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Acetate kinase plays a role in bacterial energy metabolism. It assists in the regulation of the acetyl-CoA pool an important molecule in energy production pathways. Acetate kinase does not function as part of a larger enzyme complex; rather it operates independently. In prokaryotes it participates in energy conservation by converting acetyl phosphate into ATP via substrate-level phosphorylation therefore influencing cellular energy dynamics. The enzyme's activity directly impacts acetate metabolism and the balance between anabolism and catabolism within the cell.

Pathways

Acetate kinase participates in the prokaryotic phosphotransacetylase-acetate kinase pathway which is integral to acetate metabolism and cellular respiration. This pathway collaborates closely with the TCA cycle by interacting with acetyl-CoA influencing the energy supply for cell processes. Proteins involved in related pathways include phosphotransacetylase which directly precedes acetate kinase in the pathway. Together they form a link between acetyl-CoA metabolism and energy generation impacting bacterial growth and survival.