Recombinant E. coli Protein YebF (Tagged) is a Escherichia coli K-12 Full Length protein, in the 22 to 118 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.
>90% SDS-PAGE
Escherichia coli
His tag N-Terminus
SDS-PAGE
No
A N N E T S K S V T F P K C E D L D A A G I A A S V K R D Y Q Q N R V A R W A D D Q K I V G Q A D P V A W V S L Q D I Q G K D D K W S V P L T V R G K S A D I H Y Q V S V D C K A G M A E Y Q R R
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Protein YebF, JW1836, b1847, yebF
Recombinant E. coli Protein YebF (Tagged) is a Escherichia coli K-12 Full Length protein, in the 22 to 118 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE.
>90% SDS-PAGE
Escherichia coli
His tag N-Terminus
SDS-PAGE
No
No
Escherichia coli K-12
pH: 7.2 - 7.4
Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)
A N N E T S K S V T F P K C E D L D A A G I A A S V K R D Y Q Q N R V A R W A D D Q K I V G Q A D P V A W V S L Q D I Q G K D D K W S V P L T V R G K S A D I H Y Q V S V D C K A G M A E Y Q R R
Full Length
15.8 kDa
22 to 118
Recombinant
His tag N-Terminus
Liquid
Belongs to the YebF family.
Blue Ice
-20°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
This supplementary information is collated from multiple sources and compiled automatically.
Protein YebF also known for its presence in certain gram-negative bacteria acts mainly in protein transport across the bacterial cell membrane and into the extracellular space. This small protein with a molecular weight of about 13 kDa is expressed in sites like periplasmic space. YebF undergoes a sec-independent pathway to be secreted outside of the bacterial cell. It associates with the cell membrane through interactions with outer membrane proteins facilitating its function in the transport process.
The secretion capability of Protein YebF suggests an important role in extracellular communication and bacterial survival strategies. It does not work as an isolated entity but instead often associates with other bacterial outer membrane proteins to form a complex aiding in its secretion. These interactions enhance the survival of bacteria under various extracellular challenges by possibly participating in the modulation of host interaction and nutrient acquisition.
Studies show that Protein YebF plays a role in the bacterial transport systems which are essential for nutrient uptake and waste removal. The protein associates with various transport pathways like the Sec pathway often overlapping subtly with other transporters like the TolC protein which also engages in expelling toxins and other molecules out of the cell. The role of YebF in these pathways reinforces its involvement in maintaining bacterial homeostasis and adaptation to hostile environments.
Protein YebF shows relevance to bacterial pathogenicity as its secretion function can contribute to bacterial virulence by promoting invasion or evading host immune responses. It is indirectly associated with conditions like antibiotic resistance where YebF along with proteins like TolC may aid in the expulsion of antibiotics reducing their efficacy. Understanding YebF's role in these processes helps guide potential therapeutic interventions targeting bacterial infections.
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