AB119881

Recombinant HPV18 L1 protein

Name: Recombinant HPV18 L1 protein (ab119881) | Abcam
Brand: Abcam Limited
SKU: AB119881

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(1 Publication)

Recombinant HPV18 L1 protein is a Human papillomavirus type 18 Full Length protein, in the 1 to 507 aa range, expressed in Saccharomyces cerevisiae , with >90%, suitable for SDS-PAGE, EM, WB.

View Alternative Names

Major capsid protein L1, L1

4 Images

Unknown

Electron Microscopy - Recombinant HPV18 L1 protein (AB119881)

ab119881 viewed by electron microscopy.

Supplier Data

Western blot - Recombinant HPV18 L1 protein (AB119881)

Western blot analysis of ab119881. Lane 1. ab119881 Lane 2. MWt marker

All lanes:

Western blot - Recombinant HPV18 L1 protein (ab119881)

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SDS-PAGE - Recombinant HPV18 L1 protein (AB119881)

SDS-PAGE

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SDS-PAGE - Recombinant HPV18 L1 protein (AB119881)

SDS-PAGE analysis of ab119881.

Lane 1. ab119881, 3 µg/lane
Lane 2. MWt marker 11.0, 17.0, 26.0, 34.0, 43.0, 55.0, 72.0, 95.0, 130.0, 170.0 kDa.

SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant HPV18 L1 protein (AB119881)

SDS-PAGE analysis of ab119881.

Lane 1. ab119881
Lane 2. MWt marker

Key facts

Purity

>90% SDS-PAGE

Expression system

Saccharomyces cerevisiae

Applications

WB, EM, SDS-PAGE

applications

Biologically active

Accession

P06794

Animal free

Carrier free

Yes

Species

Human papillomavirus type 18

Reconstitution

Reconstitute in 50 µL of water

Storage buffer

Constituents: 99% PBS

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" }, "EM": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"Use at a concentration of 1 - 2 µg/lane." } } }

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Sequence info

[{"sequence":"MALWRPSDNTVYLPPPSVARVVNTDDYVTRTSIFYHAGSSRLLTVGNPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTACKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNRAGTMGDTVPQSLYIKGTGMRASPGSCVYSPSPSGSIVTSDSQLFNKPYWLHKAQGHNNGVCWHNQLFVTVVDTTRSTNLTICASTQSPVPGQYDATKFKQYSRHVEEYDLQFIFQLCTITLTADVMSYIHSMNSSILEDWNFGVPPPPTTSLVDTYRFVQSVAITCQKDAAPAENKDPYDKLKFWNVDLKEKFSLDLDQYPLGRKFLVQAGLRRKPTIGPRKRSAPSATTSSKPAKRVRVRARK","proteinLength":"Full Length","predictedMolecularWeight":"56.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":507,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Saccharomyces cerevisiae ","accessionNumber":null,"tags":[]}]

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Properties and storage information

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

-20°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle|Reconstitute for long term storage

False

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Specifications

Form

Lyophilized

Additional notes

ab119881 is purified by ultracentifugation.

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General info

Function

Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.

Sequence similarities

Belongs to the papillomaviridae L1 protein family.

Subcellular localisation

Host nucleus

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Product protocols

Visit the General protocols
Visit the Troubleshooting

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Target data

See full target information Major capsid protein L1

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Human vaccines & immunotherapeutics 18:2028514 PubMed35103580

2022

Human papillomavirus infection and seroprevalence among female university students in Mexico.

Applications

Unspecified application

Species

Unspecified reactive species

Alexander Pedroza-Gonzalez,Julia Reyes-Reali,Maricela Campos-Solorzano,Eloy Moises Blancas-Diaz,Janik Adriana Tomas-Morales,Aldo Aram Hernandez-Aparicio,Daniel Montes de Oca-Samperio,Efrain Garrido,Gina Stella Garcia-Romo,Claudia Fabiola Mendez-Catala,Patricia Alvarez Ortiz,Janet Sánchez Ramos,Maria Isabel Mendoza-Ramos,Alberto Daniel Saucedo-Campos,Glustein Pozo-Molina

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Recombinant HPV18 L1 protein

Electron Microscopy - Recombinant HPV18 L1 protein (AB119881)

Western blot - Recombinant HPV18 L1 protein (AB119881)

SDS-PAGE - Recombinant HPV18 L1 protein (AB119881)

SDS-PAGE - Recombinant HPV18 L1 protein (AB119881)

Key facts

Purity

Expression system

Tags

Applications

Biologically active

Accession

Animal free

Carrier free

Species

Reconstitution

Storage buffer

Reactivity data

Sequence info

Properties and storage information

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Specifications

Form

Additional notes

General info

Function

Sequence similarities

Subcellular localisation

Product protocols

Target data

Publications (1)

Complementary Products

Secondary Antibodies

Primary Antibodies

Proteins & Peptides

Proteins & Peptides

Product promise