Recombinant Human ABP1 protein (His tag)
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Recombinant Human ABP1 protein (His tag) is a Human Full Length protein, in the 1 to 751 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
View Alternative Names
ABP, ABP1, DAO, DAO1, AOC1, Diamine oxidase [copper-containing], Diamine oxidase, Amiloride-binding protein, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO, KDAO
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human ABP1 protein (His tag) (AB276566)
SDS-PAGE analysis of ab276566
Complementary Products
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
ABP1 plays an important role in controlling cell elongation and division and it works in tandem with other auxin transporters. The protein functions within a broader receptor complex interacting with other proteins to modify plant cell physiology. Its action facilitates cell wall modification which directly influences the plant's response to environmental and endogenous signals. Through these interactions ABP1 significantly contributes to regulating the plant's phototropic and gravitropic responses.
Pathways
The operation of ABP1 integrates into the auxin signaling pathway and is associated with the regulation of gene expression. It links to TIR1 an important F-box protein in the SCF complex involved in the auxin signal transduction pathway. Together ABP1 and TIR1 coordinate to modulate the stability of transcription factors affecting downstream gene expression necessary for plant growth and development.
Specifications
Form
Lyophilized
General info
Function
Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed : 12072962, PubMed : 19764817, PubMed : 239684, PubMed : 8144586). Its preferred substrates are the diamines histamine and 1-methylhistamine and it could therefore play a role in allergic and immune responses (PubMed : 12072962). Has a broad specificity for diamines and can also act on cadaverine and putrescine, two products of amino acid catabolism (PubMed : 12072962). It could also act on polyamines, like spermidine and spermine though less efficiently, and regulate various biological processes (PubMed : 12072962, PubMed : 239684).
Sequence similarities
Belongs to the copper/topaquinone oxidase family.
Post-translational modifications
N-glycosylated.. Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
Target data
Product promise
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