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AB171507

Recombinant Human ACBD6 protein (His tag N-Terminus)

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Recombinant Human ACBD6 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 282 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

Acyl-CoA-binding domain-containing protein 6, ACBD6

1 Images
SDS-PAGE - Recombinant Human ACBD6 protein (His tag N-Terminus) (AB171507)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human ACBD6 protein (His tag N-Terminus) (AB171507)

15% SDS-PAGE analysis of ab171507 (3μg).

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Q9BR61

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMASSFLPAGAITGDSGGELSSGDDSGEVEFPHSPEIEETSCLAELFEKAAAHLQGLIQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPGWNPQIPEKKGKEANTGFGGPVISSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQRHTTGKA","proteinLength":"Full Length","predictedMolecularWeight":"33.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":282,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9BR61","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ACBD6 also known as Acyl-CoA binding domain-containing protein 6 is a protein with a molecular weight of approximately 32 kDa. It acts by binding to acyl-CoA molecules and impacting cellular lipid metabolism. Widely expressed in human tissues ACBD6 shows notably higher expression in the heart and testis. This protein plays an important role in maintaining lipid homeostasis within cells.
Biological function summary

ACBD6 modulates lipid signalling processes and participates in cellular lipid droplet formation. It is part of the larger acyl-CoA binding protein family which is known for regulating lipid metabolism. By interacting with these lipid molecules ACBD6 influences cellular energy dynamics and storage capacity. In some contexts it forms complexes with other proteins to modulate lipid processing and serve metabolic functions.

Pathways

ACBD6 integrates into lipid metabolism pathways where it affects fatty acid binding and transport. The protein interacts with components of the triacylglycerol biosynthesis pathway making connections with members like the lipase family. ACBD6’s relationships with these pathways highlight its role in the cellular process of storing and utilizing lipids for energy and structural purposes.

ACBD6 has been linked to diseases related to dysregulated lipid metabolism such as obesity and type 2 diabetes. Dysfunctions in ACBD6 activity can contribute to abnormal lipid accumulation and impaired energy balance. It connects to metabolic syndrome through pathways shared with proteins like LPL known for their roles in lipid metabolism disorders. Understanding the impact of ACBD6 in these conditions can help in developing targeted therapeutic strategies.
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Specifications

Form

Liquid

Additional notes

ab171507 is purified using conventional chromatography techniques.

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General info

Function

Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18 : 1-CoA, lower affinity for unsaturated C20 : 4-CoA, and very weak affinity for saturated C16 : 0-CoA. Does not bind fatty acids. Plays a role in protein N-myristoylation (PubMed : 37951597).

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Product protocols

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Target data

Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18 : 1-CoA, lower affinity for unsaturated C20 : 4-CoA, and very weak affinity for saturated C16 : 0-CoA. Does not bind fatty acids. Plays a role in protein N-myristoylation (PubMed : 37951597).
See full target information ACBD6
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