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AB276432

Recombinant Human ACRV1 protein (His tag)

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Recombinant Human ACRV1 protein (His tag) is a Human Full Length protein, in the 22 to 265 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

Acrosomal protein SP-10, Acrosomal vesicle protein 1, ACRV1

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SDS-PAGE - Recombinant Human ACRV1 protein (His tag) (AB276432)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human ACRV1 protein (His tag) (AB276432)

SDS-PAGE analysis of ab276432

Key facts

Purity

>90% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P26436

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: 100% PBS

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"QPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPISSTSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI","proteinLength":"Full Length","predictedMolecularWeight":"27.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":265,"aminoAcidStart":22,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"P26436","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

ACRV1 also known as acidic epididymal glycoprotein (AEG) is a protein that plays a role in reproductive biology. This protein has a molecular mass of approximately 24 kDa. Expression of ACRV1 mainly occurs in the testis more specifically in germ cells during spermatogenesis. Due to its specialized expression ACRV1 serves functions related to sperm development and maturation.
Biological function summary

Acidic epididymal glycoprotein (AEG) contributes to the stability and function of the acrosome a cap-like structure in sperm cells necessary for fertilization. ACRV1 is part of a larger protein complex involved in this process ensuring structural integrity and facilitating sperm-egg interaction. The acrosome plays a critical role in releasing enzymes that allow sperm to penetrate the egg’s outer layer enabling fertilization.

Pathways

Sperm maturation and fertilization processes rely on the presence of ACRV1. This protein is involved in the spermatogenesis pathway which is essential for producing functional and viable sperm. ACRV1 interacts with alpha-lactalbumin and protamines during this pathway to maintain chromatin stability and enable appropriate sperm head structure changes important for successful fertilization.

Abnormalities in ACRV1 expression or function can affect male fertility potentially leading to infertility conditions such as azoospermia. Defects in ACRV1 can disrupt normal sperm development contributing to issues with acrosome formation. ACRV1 is associated with other sperm-specific proteins like protamine 1 and cathepsin L which are implicated in compromised spermatozoa function and male reproductive disorders.
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Specifications

Form

Lyophilized

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General info

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Product protocols

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Target data

See full target information Acrosomal protein SP-10
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Product promise

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