Recombinant Human ALDH6A1 protein (His tag N-Terminus)
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Recombinant Human ALDH6A1 protein (His tag N-Terminus) is a Human Full Length protein, in the 34 to 535 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.
View Alternative Names
MMSDH, ALDH6A1, Aldehyde dehydrogenase family 6 member A1, Malonate-semialdehyde dehydrogenase [acylating]
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human ALDH6A1 protein (AB201884)
15% SDS PAGE analysis of ab201884 (3 μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
ALDH6A1 contributes to cellular detoxification and energy production by participating in the breakdown of aldehydes which are toxic if accumulated. It is a part of the mitochondrial aldehyde dehydrogenase complex working alongside other enzymes for efficient catalysis. The enzyme's activity helps maintain cellular redox balance and supports energy metabolism directly impacting cellular function.
Pathways
ALDH6A1 plays a role within the propanoate metabolism and valine degradation processes. Through these pathways ALDH6A1 connects to proteins such as the branched-chain-amino-acid aminotransferase (BCAT) and propionyl-CoA carboxylase (PCC). These interactions facilitate the breakdown of amino acids into substrates that enter the citric acid cycle contributing to cellular energy generation.
Specifications
Form
Liquid
Additional notes
ab201884 was purified by using conventional chromatography techniques.
General info
Function
Malonate and methylmalonate semialdehyde dehydrogenase involved in the catabolism of valine, thymine, and compounds catabolized by way of beta-alanine, including uracil and cytidine.
Sequence similarities
Belongs to the aldehyde dehydrogenase family.
Subcellular localisation
Mitochondrion
Target data
Complementary Products
Product promise
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