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AB164545

Recombinant Human ALKBH7 protein (GST tag N-Terminus)

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Recombinant Human ALKBH7 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 221 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

ABH7, SPATA11, UNQ6002/PRO34564, ALKBH7, Alkylated DNA repair protein alkB homolog 7, Spermatogenesis cell proliferation-related protein, Spermatogenesis-associated protein 11, pre-tRNA N1-methyl adenine demethylase ALKBH7, pre-tRNA N2-dimethyl guanosine demethylase ALKBH7

1 Images
SDS-PAGE - Recombinant Human ALKBH7 protein (GST tag N-Terminus) (AB164545)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human ALKBH7 protein (GST tag N-Terminus) (AB164545)

ab164545 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB

applications

Biologically active

No

Accession

Q9BT30

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MAGTGLLALRTLPGPSWVRGSGPSVLSRLQDAAVVRPGFLSTAEEETLSRELEPELRRRRYEYDHWDAAIHGFRETEKSRWSEASRAILQRVQAAAFGPGQTLLSSVHVLDLEARGYIKPHVDSIKFCGATIAGLSLLSPSVMRLVHTQEPGEWLELLLEPGSLYILRGSARYDFSHEILRDEESFFGERRIPRGRRISVICRSLPEGMGPGESGQPPPAC","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":221,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9BT30","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

RNA demethylase that demethylates N(2)-dimethylguanosine and N(1)-methyladenosine within mitochondrial pre-tRNA regions. This demethylation activity plays a crucial role in regulating the processing of nascent polycistronic mitochondrial RNA, thereby influencing mitochondrial gene expression and overall mitochondrial activity (PubMed : 34253897). In response to extensive DNA damage is required for programmed necrosis induced by alkylation and oxidation. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed : 23666923). Involved in fatty acid metabolism (By similarity).

Sequence similarities

Belongs to the alkB family.

Subcellular localisation

Mitochondrion matrix

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Product protocols

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Target data

RNA demethylase that demethylates N(2)-dimethylguanosine and N(1)-methyladenosine within mitochondrial pre-tRNA regions. This demethylation activity plays a crucial role in regulating the processing of nascent polycistronic mitochondrial RNA, thereby influencing mitochondrial gene expression and overall mitochondrial activity (PubMed : 34253897). In response to extensive DNA damage is required for programmed necrosis induced by alkylation and oxidation. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed : 23666923). Involved in fatty acid metabolism (By similarity).
See full target information ALKBH7
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