Recombinant Human ALR/HPO protein (His tag)
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Recombinant Human ALR/HPO protein (His tag) is a Human Fragment protein, in the 1 to 125 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
View Alternative Names
ALR, HERV1, HPO, GFER, FAD-linked sulfhydryl oxidase ALR, Augmenter of liver regeneration, Hepatopoietin, hERV1
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human ALR/HPO protein (His tag) (AB276645)
SDS-PAGE analysis of ab276645
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Lyophilized
General info
Function
Isoform 1. FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.. Isoform 2. May act as an autocrine hepatotrophic growth factor promoting liver regeneration.
Subcellular localisation
Mitochondrion intermembrane space
Target data
Product promise
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