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AB128452

Recombinant Human Annexin A8 like2 protein (His tag N-Terminus)

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Recombinant Human Annexin A8 like2 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 327 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

ANXA8L2, ANXA8L1, Annexin A8-like protein 1

1 Images
SDS-PAGE - Recombinant Human Annexin A8 like2 protein (His tag N-Terminus) (AB128452)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human Annexin A8 like2 protein (His tag N-Terminus) (AB128452)

15% SDS-PAGE showing ab128452 at approximately 39.4 kDa (3µg).

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Q5VT79

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Not currently tested for endotoxin levels.
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSHMAWWKAWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDLYAAGENIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSDP","proteinLength":"Full Length","predictedMolecularWeight":"39.4 kDa","actualMolecularWeight":null,"aminoAcidEnd":327,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q5VT79","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Annexin A8 like2 also known as ANXA8L2 is a member of the annexin family of calcium-dependent phospholipid-binding proteins. This protein weighs approximately 37 kDa and is expressed in various tissues with significant expression documented in the placenta and certain cancerous tissues. Annexin A8 like2 plays a role in cellular processes like membrane organization and signal transduction contributing to its functional complexity.
Biological function summary

Annexin family proteins including Annexin A8 like2 facilitate the cellular functions by forming a complex with membranes under influence of calcium ions. Annexin A8 like2 participates in membrane dynamics and vesicle trafficking. Through its interactions it impacts several cellular activities which are necessary for maintaining cellular equilibrium and response to external signals.

Pathways

Annexin A8 like2 intersects notably with the cell cycle and apoptosis pathways. Within these it collaborates with proteins such as Annexin A1 and Annexin A5 to modulate processes that control cell division and programmed cell death. Its relation to these pathways shows its involvement in key regulatory mechanisms that ensure proper cellular function and response to stressors.

Annexin A8 like2 shows connection to cancer particularly in cancers of epithelial origin and inflammatory disorders. Its expression in cancerous tissues suggests a role in tumor progression possibly through its influence on cell proliferation and apoptosis. An association with inflammatory disorders involves interactions with annexin family proteins including Annexin A1 contributing to the inflammatory response and immune modulation.
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Specifications

Form

Liquid

Additional notes

ab128452 is purified using conventional chromatography techniques (anion exchange and gel filtration)

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General info

Sequence similarities

Belongs to the annexin family.

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Product protocols

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Target data

See full target information ANXA8L1
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