Recombinant Human Annexin A8 like2 protein is a Human Full Length protein, in the 1 to 327 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.
Images
Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M G S H M A W W K A W I E Q E G V T V K S S S H F N P D P D A E T L Y K A M K G I G T N E Q A I I D V L T K R S N T Q R Q Q I A K S F K A Q F G K D L T E T L K S E L S G K F E R L I V A L M Y P P Y R Y E A K E L H D A M K G L G T K E G V I I E I L A S R T K N Q L R E I M K A Y E E D Y G S S L E E D I Q A D T S G Y L E R I L V C L L Q G S R D D V S S F V D P A L A L Q D A Q D L Y A A G E N I R G T D E M K F I T I L C T R S A T H L L R V F E E Y E K I A N K S I E D S I K S E T H G S L E E A M L T V V K C T Q N L H S Y F A E R L Y Y A M K G A G T R D G T L I R N I V S R S E I D L N L I K C H F K K M Y G K T L S S M I M E D T S G D Y K N A L L S L V G S D P
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Alternative names
ANXA8L2, ANXA8L1, Annexin A8-like protein 1
Recombinant Human Annexin A8 like2 protein is a Human Full Length protein, in the 1 to 327 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.
Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
- Accession
- Q5VT79-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M G S H M A W W K A W I E Q E G V T V K S S S H F N P D P D A E T L Y K A M K G I G T N E Q A I I D V L T K R S N T Q R Q Q I A K S F K A Q F G K D L T E T L K S E L S G K F E R L I V A L M Y P P Y R Y E A K E L H D A M K G L G T K E G V I I E I L A S R T K N Q L R E I M K A Y E E D Y G S S L E E D I Q A D T S G Y L E R I L V C L L Q G S R D D V S S F V D P A L A L Q D A Q D L Y A A G E N I R G T D E M K F I T I L C T R S A T H L L R V F E E Y E K I A N K S I E D S I K S E T H G S L E E A M L T V V K C T Q N L H S Y F A E R L Y Y A M K G A G T R D G T L I R N I V S R S E I D L N L I K C H F K K M Y G K T L S S M I M E D T S G D Y K N A L L S L V G S D P
- Accession
- Q5VT79
- Protein length
- Full Length
- Predicted molecular weight
- 39.4 kDa
- Amino acids
- 1 to 327
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
- Additional notes
ab128452 is purified using conventional chromatography techniques (anion exchange and gel filtration)
General info
- Sequence similarities
Belongs to the annexin family.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Not currently tested for endotoxin levels.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
Annexin A8 like2 also known as ANXA8L2 is a member of the annexin family of calcium-dependent phospholipid-binding proteins. This protein weighs approximately 37 kDa and is expressed in various tissues with significant expression documented in the placenta and certain cancerous tissues. Annexin A8 like2 plays a role in cellular processes like membrane organization and signal transduction contributing to its functional complexity.
- Biological function summary
Annexin family proteins including Annexin A8 like2 facilitate the cellular functions by forming a complex with membranes under influence of calcium ions. Annexin A8 like2 participates in membrane dynamics and vesicle trafficking. Through its interactions it impacts several cellular activities which are necessary for maintaining cellular equilibrium and response to external signals.
- Pathways
Annexin A8 like2 intersects notably with the cell cycle and apoptosis pathways. Within these it collaborates with proteins such as Annexin A1 and Annexin A5 to modulate processes that control cell division and programmed cell death. Its relation to these pathways shows its involvement in key regulatory mechanisms that ensure proper cellular function and response to stressors.
- Associated diseases and disorders
Annexin A8 like2 shows connection to cancer particularly in cancers of epithelial origin and inflammatory disorders. Its expression in cancerous tissues suggests a role in tumor progression possibly through its influence on cell proliferation and apoptosis. An association with inflammatory disorders involves interactions with annexin family proteins including Annexin A1 contributing to the inflammatory response and immune modulation.
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1 product image
SDS-PAGE - Recombinant Human Annexin A8 like2 protein (ab128452)
15% SDS-PAGE showing ab128452 at approximately 39.4 kDa (3µg).
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