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AB132786

Recombinant Human APMAP protein

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Recombinant Human APMAP protein is a Human Full Length protein, in the 1 to 416 aa range, expressed in Wheat germ, suitable for SDS-PAGE, ELISA, WB.

View Alternative Names

C20orf3, UNQ1869/PRO4305, APMAP, Adipocyte plasma membrane-associated protein, Protein BSCv

1 Images
SDS-PAGE - Recombinant Human APMAP protein (AB132786)
  • SDS-PAGE

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SDS-PAGE - Recombinant Human APMAP protein (AB132786)

12.5% SDS-PAGE analysis of ab132786 stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

Tag free

Applications

SDS-PAGE, ELISA, WB

applications

Biologically active

No

Accession

Q9HDC9

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MSEADGLRQRRPLRPQVVTDDDGQAPEAKDGSSFSGRVFRVTFLMLAVSLTVPLLGAMMLLESPIDPQPLSFKEPPLLLGVLHPNTKLRQAERLFENQLVGPESIAHIGDVMFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPVCGRPLGIRAGPNGTLFVADAYKGLFEVNPWKREVKLLLSSETPIEGKNMSFVNDLTVTQDGRKIYFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTREVKVLLDQLRFPNGVQLSPAEDFVLVAETTMARIRRVYVSGLMKGGADLFVENMPGFPDNIRPSSSGGYWVGMSTIRPNPGFSMLDFLSERPWIKRMIFKLFSQETVMKFVPRYSLVLELSDSGAFRRSLHDPDGLVATYISEVHEHDGHLYLGSFRSPFLCRLSLQAV","proteinLength":"Full Length","predictedMolecularWeight":"72.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":416,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9HDC9","tags":[]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

APMAP also known as adipocyte plasma membrane-associated protein is an integral membrane protein that weighs approximately 45 kDa. APMAP localizes primarily in adipose tissues and hepatocytes. This protein resides within both the plasma membrane and intracellular compartments. APMAP participates in lipid metabolism through its interactions with various protein complexes. Its expression levels vary across different tissues reflecting a specialized role in certain physiological functions.
Biological function summary

APMAP functions within the modulation of lipid homeostasis especially in adipocytes. It shows involvement in triglyceride metabolism by regulating enzyme activity responsible for lipid turnover. APMAP acts as a part of a protein complex that includes enzymes affecting lipid storage and release. Through such interactions APMAP influences key biological processes that maintain lipid balance supporting energy homeostasis in mammals.

Pathways

APMAP integrates into the lipid metabolic pathway particularly those impacting triglyceride storage and hydrolysis. APMAP associates with proteins like perilipin which also participate in lipid droplet formation and breakdown. Additionally APMAP's involvement with AMP-activated protein kinase (AMPK) signaling influences cellular energy status linking it to pathways controlling metabolism and energy sensing.

APMAP shows association with metabolic syndrome and type 2 diabetes. Its role in lipid metabolism connects APMAP to insulin signaling pathways where altered expression or function may contribute to these metabolic disorders. APMAP's relationship with adiponectin a protein with anti-diabetic properties indicates its potential impact on glucose metabolism dysregulation. Understanding APMAP's function helps unravel molecular underpinnings of metabolic diseases offering insights for targeted therapeutic approaches.
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Specifications

Form

Liquid

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General info

Function

Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation.

Sequence similarities

Belongs to the strictosidine synthase family.

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Product protocols

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Target data

Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation.
See full target information APMAP
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