Recombinant Human BAP31 protein
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Recombinant Human BAP31 protein is a Human Full Length protein, in the 1 to 246 aa range, expressed in Wheat germ, suitable for SDS-PAGE, ELISA, WB.
View Alternative Names
BAP31, DXS1357E, BCAP31, B-cell receptor-associated protein 31, BCR-associated protein 31, Bap31, 6C6-AG tumor-associated antigen, Protein CDM, p28
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human BAP31 protein (AB132144)
12.5% SDS-PAGE analysis of ab132144 stained with Coomassie Blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Functions as a chaperone protein (PubMed : 18287538, PubMed : 9396746). Is one of the most abundant endoplasmic reticulum (ER) proteins (PubMed : 18287538, PubMed : 9396746). Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD) (PubMed : 18287538, PubMed : 9396746). Also serves as a cargo receptor for the export of transmembrane proteins (By similarity). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40 (PubMed : 31206022). In response to ER stress, delocalizes from the ER-mitochondria contact sites and binds BCL2 (PubMed : 31206022). May be involved in CASP8-mediated apoptosis (PubMed : 10958671).
Sequence similarities
Belongs to the BCAP29/BCAP31 family.
Post-translational modifications
Cleaved by CASP8 and other caspases.
Target data
Product promise
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