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AB243796

Recombinant human BCMA protein (Active)

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Recombinant human BCMA protein (Active) is a Human Fragment BCMA/TNFRSF17 protein in the 5 to 54 aa range with >98% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE, Functional studies and HPLC. The predicted molecular weight of ab243796 recombinant protein is 5.4 kDa.

- Save time and ensure accurate results - use our recombinant BCMA/TNFRSF17 protein as a control
- Tag-free, ensuring its native conformation
- Optimal protein bioactivity, stability and reproducibility

View Alternative Names

CD269, BCM, BCMA, TNFRSF17, Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein

1 Images
SDS-PAGE - Recombinant human BCMA protein (Active) (AB243796)
  • SDS-PAGE

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SDS-PAGE - Recombinant human BCMA protein (Active) (AB243796)

SDS-PAGE analysis of ab243796

Key facts

Purity

>98% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

Escherichia coli

Tags

Tag free

Applications

SDS-PAGE, HPLC, FuncS

applications

Biologically active

Yes

Biological activity

Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40 ng/ml, corresponding to a specific activity of >2.5x104 IU/mg in the presence of 100 ng/ml human APRIL.

Accession

Q02223

Animal free

No

Carrier free

No

Species

Human

Reconstitution

Reconstitute in water or 0.1% BSA aqueous buffer

Storage buffer

Constituents: 0.1% Trifluoroacetic acid, 0.01% Acetonitrile

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Ensure the validity of your result using our recombinant human BCMA protein (Active) ab243796 as a positive control in SDS-PAGE and HPLC.

Check out our protein gel staining guide for SDS-PAGE here

Our bioactive recombinant BCMA/TNFRSF17 protein ab243796 is ideal to study BCMA /TNFRSF17 in cancer biology and unravel its role in B-cell maturation and tumorigenesis.
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Sequence info

[{"sequence":"AGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVKGTNA","proteinLength":"Fragment","predictedMolecularWeight":"5.4 kDa","actualMolecularWeight":null,"aminoAcidEnd":54,"aminoAcidStart":5,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q02223","tags":[]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
True
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Specifications

Form

Lyophilized

Additional notes

>98% as determined by HPLC.

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General info

Function

The protein expressed by the TNFRSF17 gene acts as a receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. It promotes B-cell survival and plays a role in regulating humoral immunity, while also activating NF-kappa-B and JNK. This supplementary information is collated from multiple sources and compiled automatically.

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Product protocols

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Target data

The protein expressed by the TNFRSF17 gene acts as a receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. It promotes B-cell survival and plays a role in regulating humoral immunity, while also activating NF-kappa-B and JNK. This supplementary information is collated from multiple sources and compiled automatically.
See full target information TNFRSF17
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Complementary Products

Primary Antibodies

AB253242

Anti-BCMA antibody [EPR22457-260]

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Immunocytochemistry/ Immunofluorescence - Anti-BCMA antibody [EPR22457-260] (AB253242)

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Assay Kits

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Human BCMA ELISA Kit

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ELISA - Human BCMA ELISA Kit (AB263875)

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Secondary Antibodies

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Proteins & Peptides

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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