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AB152736

Recombinant Human BI-1 protein (GST tag N-Terminus)

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Recombinant Human BI-1 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 237 aa range, expressed in Wheat germ, suitable for SDS-PAGE, ELISA, WB.

View Alternative Names

BI1, TEGT, TMBIM6, Bax inhibitor 1, BI-1, Testis-enhanced gene transcript protein, Transmembrane BAX inhibitor motif-containing protein 6

1 Images
SDS-PAGE - Recombinant Human BI-1 protein (GST tag N-Terminus) (AB152736)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human BI-1 protein (GST tag N-Terminus) (AB152736)

12.5% SDS-PAGE analysis of ab152736 stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

SDS-PAGE, WB, ELISA

applications

Biologically active

No

Accession

P55061

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

This product was previously labelled as Bax inhibitor 1.
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Sequence info

[{"sequence":"MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMLVAAAGAYVHMVTHFIQAGLLSALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMGTAMTFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVVMCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMILAMNEKDKKKEKK","proteinLength":"Full Length","predictedMolecularWeight":"51.81 kDa","actualMolecularWeight":null,"aminoAcidEnd":237,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"P55061","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

Endoplasmic reticulum (ER)-resident protein that confers cellular protection as an anti-apoptotic protein by limiting multiple stress-inducing pathways surrounding the endoplasmic reticulum and mitochondria (PubMed : 21075086, PubMed : 21068390). Inhibits the activities of the key sensor for the endoplasmic reticulum unfolded protein response IRE1alpha/ERN1 both directly and by blocking BAX/BAK binding (PubMed : 19328063). Modulates ER calcium homeostasis by acting as a calcium-leak channel (PubMed : 22128171). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (By similarity).

Sequence similarities

Belongs to the BI1 family.

Post-translational modifications

Ubiquitinated by BFAR, leading to proteasomal degradation.

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Product protocols

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Target data

Endoplasmic reticulum (ER)-resident protein that confers cellular protection as an anti-apoptotic protein by limiting multiple stress-inducing pathways surrounding the endoplasmic reticulum and mitochondria (PubMed : 21075086, PubMed : 21068390). Inhibits the activities of the key sensor for the endoplasmic reticulum unfolded protein response IRE1alpha/ERN1 both directly and by blocking BAX/BAK binding (PubMed : 19328063). Modulates ER calcium homeostasis by acting as a calcium-leak channel (PubMed : 22128171). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (By similarity).
See full target information TMBIM6
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Product promise

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