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Recombinant Human BIN2 protein is a Human Fragment protein, in the 1 to 244 aa range, expressed in Escherichia coli, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.

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Key facts

Purity
>95% SDS-PAGE
Endotoxin level
< 1 EU/µg
Expression system
Escherichia coli
Tags
His tag N-Terminus
Applications
SDS-PAGE
Biologically active
No

Amino acid sequence

M A E G K A G G A A G L F A K Q V Q K K F S R A Q E K V L Q K L G K A V E T K D E R F E Q S A S N F Y Q Q Q A E G H K L Y K D L K N F L S A V K V M H E S S K R V S E T L Q E I Y S S E W D G H E E L K A I V W N N D L L W E D Y E E K L A D Q A V R T M E I Y V A Q F S E I K E R I A K R G R K L V D Y D S A R H H L E A V Q N A K K K D E A K T A K A E E E F N K A Q T V F E D L N Q E L L E E L P I L Y N S R I G C Y V T I F Q N I S N L R D V F Y R E M S K L N H N L Y E V M S K L E K Q H S N

Reactivity data

Application
SDS-PAGE
Reactivity
Reacts
Dilution info
-
Notes

-

Target data

Function

Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.

Alternative names

BRAP1, BIN2, Bridging integrator 2, Breast cancer-associated protein 1

Recommended products

Recombinant Human BIN2 protein is a Human Fragment protein, in the 1 to 244 aa range, expressed in Escherichia coli, with >95% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.

Key facts

Purity
>95% SDS-PAGE
Endotoxin level
< 1 EU/µg
Expression system
Escherichia coli
Applications
SDS-PAGE
Accession
Q9UBW5-1
Animal free
No
Species
Human
Reconstitution
Reconstitute in PBS
Concentration
Loading...
Storage buffer

pH: 8
Constituents: 99% Phosphate Buffer, 0.88% Sodium chloride

Sequence info

Amino acid sequence

M A E G K A G G A A G L F A K Q V Q K K F S R A Q E K V L Q K L G K A V E T K D E R F E Q S A S N F Y Q Q Q A E G H K L Y K D L K N F L S A V K V M H E S S K R V S E T L Q E I Y S S E W D G H E E L K A I V W N N D L L W E D Y E E K L A D Q A V R T M E I Y V A Q F S E I K E R I A K R G R K L V D Y D S A R H H L E A V Q N A K K K D E A K T A K A E E E F N K A Q T V F E D L N Q E L L E E L P I L Y N S R I G C Y V T I F Q N I S N L R D V F Y R E M S K L N H N L Y E V M S K L E K Q H S N
Accession
Q9UBW5
Protein length
Fragment
Predicted molecular weight
30 kDa
Amino acids
1 to 244
Nature
Recombinant
Tags
His tag N-Terminus

Specifications

Form
Lyophilized
Additional notes

The purity of ab152048 is greater than 95%, as determined by reducing SDS-PAGE. It was lyophilized from an 0.2 µM filtered solution.

General info

Function

Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
A few weeks
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C

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