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AB94350

Recombinant human BMP9 protein (Active)

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Recombinant human BMP9 protein (Active) is a Human Full Length protein, in the 320 to 429 aa range, expressed in CHO cells, with >95%, suitable for SDS-PAGE, HPLC, FuncS.

View Alternative Names

BMP9, GDF2, Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9

Key facts

Purity

>95% SDS-PAGE

Expression system

CHO cells

Tags

Tag free

Applications

HPLC, FuncS, SDS-PAGE

applications

Biologically active

Yes

Biological activity

Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.9 ng/ml.

Accession

Q9UK05

Animal free

No

Carrier free

No

Species

Human

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Sequence info

[{"sequence":"SAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGCR","proteinLength":"Full Length","predictedMolecularWeight":"24.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":429,"aminoAcidStart":320,"nature":"Recombinant","expressionSystem":"CHO cells","accessionNumber":"Q9UK05","tags":[]}]

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
True

Specifications

Form

Lyophilized

Additional notes

Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).

General info

Function

Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

Sequence similarities

Belongs to the TGF-beta family.

Post-translational modifications

A reversible disulfide bond can be formed between the two subunits in the homodimer; this has no effect on GDF2 activity.

Product protocols

Target data

Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.
See full target information GDF2

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