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AB276517

Recombinant Human C12orf53 protein (Fc Chimera)

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Recombinant Human C12orf53 protein (Fc Chimera) is a Human Fragment protein, in the 1 to 178 aa range, expressed in HEK 293 cells, with >96%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

C12orf53, PANP, UNQ828/PRO1755, PIANP, PILR alpha-associated neural protein, PILR-associating neural protein, Paired immunoglobin-like type 2 receptor-associating neural protein

1 Images
SDS-PAGE - Recombinant Human C12orf53 protein (Fc Chimera) (AB276517)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human C12orf53 protein (Fc Chimera) (AB276517)

SDS-PAGE analysis of ab276517

Key facts

Purity

>96% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

Fc tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q8IYJ0

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: PBS

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Sequence info

[{"linker":null,"sequence":"MESRMWPALLLSHLLPLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPHPNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDP","proteinLength":"Fragment","predictedMolecularWeight":"42.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":178,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q8IYJ0","tags":[{"tag":"Fc","terminus":"C-Terminus"}]}]

Properties and storage information

Form
Lyophilized
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C12orf53 also known as Chromosome 12 Open Reading Frame 53 is a lesser-known protein that weighs approximately 21 kDa. Scientists have not completely understood its mechanical function but it consists of at least 177 amino acids forming its structure. Expression of C12orf53 appears in various tissues like the kidney liver and testis which suggests a broad spectrum of activity throughout the human body. Its expression pattern also indicates a potential role beyond tissue-specific functions.
Biological function summary

There is little information regarding C12orf53's role but researchers speculate involvement in cellular processes due to its expression in vital organs. It might integrate into larger protein complexes or pathways contributing to cellular maintenance or metabolism. The lack of detailed functional studies makes its precise biological role unclear at this moment; however scientists are actively investigating to fill these gaps.

Pathways

C12orf53 possibly participates in pathways related to fundamental cellular processes but definitive pathways remain unidentified due to the lack of comprehensive studies. Exploration of interactions with proteins like those involved in cellular signaling or metabolic pathways is currently a focus. Understanding these interactions will help uncover the broader network within which C12orf53 functions.

Research is still ongoing to establish clear connections between C12orf53 and specific conditions. However emerging data suggest possible links to metabolic disorders due to its expression in the liver and other metabolic tissues. Additionally its potential interaction with proteins involved in cellular stress responses could indicate relevance to pathologies where such dynamics are disrupted. Further research and clinical studies will help clarify these associations.

General info

Function

Acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation.

Post-translational modifications

O-glycosylation at Thr-140 is essential for recognition by PILRA.

Product protocols

Target data

Acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation.
See full target information PIANP

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