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AB168069

Recombinant Human C19orf50 protein

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Recombinant Human C19orf50 protein is a Human Full Length protein, in the 1 to 179 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

C19orf50, KXD1, KxDL motif-containing protein 1

1 Images
SDS-PAGE - Recombinant Human C19orf50 protein (AB168069)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human C19orf50 protein (AB168069)

3 μg ab168069 on 15% SDS-PAGE

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Q9BQD3

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMDLPDSASRVFCGRILSMVNTDDVNAIILAQKNMLDRFEKTNEMLLNFNNLSSARLQQMSERFLHHTRTLVEMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEASFLEEEDEDPIPPSTTTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHVQPGSPAINGRSQTDDEEMTGE","proteinLength":"Full Length","predictedMolecularWeight":"22.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":179,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9BQD3","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C19orf50 also known as Chromosome 19 Open Reading Frame 50 is a protein that has a molecular weight of approximately 17 kDa. The protein expresses in various tissues throughout the body indicating a broad role within cellular activities. Though its exact mechanical function isn’t fully determined it may interact with other proteins due to its expression levels across different systems.
Biological function summary

Proteins associated with C19orf50 engage in cellular development and maintenance. Evidence suggests it acts as part of a protein complex influencing key processes within cells. Its function may intersect with regulatory mechanisms affecting cellular growth and differentiation.

Pathways

Cellular processes involving C19orf50 are linked with cellular signal transduction and metabolic pathways. The protein potentially interacts with key players in these pathways such as mTOR signaling. This connection aids in modulating cellular energy balance with influences observed alongside proteins like AMPK which play a role in energy homeostasis and cellular response to stress.

C19orf50's role involves pathogeneses related to metabolic dysfunction and proliferative disorders. In the context of type 2 diabetes evidence suggests a possible interaction with insulin signaling proteins contributing to impaired glucose metabolism. Additionally research implicates its regulatory influence in some cancers possibly through modulation of pathways involving tumor suppressor proteins like p53.
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Specifications

Form

Liquid

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General info

Function

As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed : 25898167). May be involved in the biogenesis of lysosome-related organelles such as melanosomes (By similarity).

Sequence similarities

Belongs to the KXD1 family.

Subcellular localisation

Lysosome membrane

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed : 25898167). May be involved in the biogenesis of lysosome-related organelles such as melanosomes (By similarity).
See full target information KXD1
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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