Recombinant Human C1orf41 protein is a Human protein, in the 1 to 144 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.
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Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M R K I D L C L S S E G S E V I L A T S S D E K H P P E N I I D G N P E T F W T T T G M F P Q E F I I C F H K H V R I E R L V I Q S Y F V Q T L K I E K S T S K E P V D F E Q W I E K D L V H T E G Q L Q N E E I V A H D G S A T Y L R F I I V S A F D H F A S V H S V S A E G T V V S N L S S
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation (By similarity).
Alternative names
C1orf41, HSPB11, HSPC034, IFT25, Intraflagellar transport protein 25 homolog, Heat shock protein beta-11, Heat shock protein family B member 11, Placental protein 25, Hspb11, PP25
Recommended products
Recombinant Human C1orf41 protein is a Human protein, in the 1 to 144 aa range, expressed in Escherichia coli, with >90% purity and suitable for SDS-PAGE, MS.
Key facts
- Purity
- >90% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
- Accession
- Q9Y547-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.316% Tris HCl, 0.0308% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M R K I D L C L S S E G S E V I L A T S S D E K H P P E N I I D G N P E T F W T T T G M F P Q E F I I C F H K H V R I E R L V I Q S Y F V Q T L K I E K S T S K E P V D F E Q W I E K D L V H T E G Q L Q N E E I V A H D G S A T Y L R F I I V S A F D H F A S V H S V S A E G T V V S N L S S
- Accession
- Q9Y547
- Predicted molecular weight
- 18.5 kDa
- Amino acids
- 1 to 144
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
- Additional notes
ab107137 is purified using conventional chromatography techniques.
General info
- Function
Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation (By similarity).
- Sequence similarities
Belongs to the IFT25 family.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human C1orf41 protein (ab107137)
15% SDS-PAGE showing ab107137 (3μg).
Downloads
Product protocols
- Visit the general protocols
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