Recombinant Human C1s protein (GST tag N-Terminus)
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Recombinant Human C1s protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 688 aa range, expressed in Wheat germ, suitable for SDS-PAGE, ELISA, WB.
View Alternative Names
Complement C1s subcomponent, C1 esterase, Complement component 1 subcomponent s, C1S
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human C1s protein (GST tag N-Terminus) (AB116902)
12.5% SDS-PAGE showing ab116902 at approximately 101.75 kDa stained with Coomassie Blue.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. Cleaves also IGFBP5 and thereby inhibits the trophic effects of IGF1.
Sequence similarities
Belongs to the peptidase S1 family.
Post-translational modifications
The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Target data
Product promise
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