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AB177597

Recombinant Human C3orf10 protein

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Recombinant Human C3orf10 protein is a Human Full Length protein, in the 1 to 75 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

C3orf10, HSPC300, MDS027, BRK1, Protein BRICK1

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Q8WUW1

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMAGQEDPVQREIHQDWANREYIEIITSSIKKIADFLNSFDMSCRSRLATLNEKLTALERRIEYIEARVTKGETLT","proteinLength":"Full Length","predictedMolecularWeight":"11 kDa","actualMolecularWeight":null,"aminoAcidEnd":75,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q8WUW1","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C3orf10 also known as ARMH4 or Armadillo Repeat Containing 4 encodes a protein with a currently limited mechanical description. This protein weighs approximately 54 kDa and is expressed in multiple tissues notably in the brain and skeletal muscle. Studies indicate it may play a role in cellular architecture or signal transduction but exact mechanical roles require further investigation.
Biological function summary

The protein product of C3orf10 may participate in cellular structural organization or intracellular signaling. Evidence suggests it functions as part of a larger protein complex though not extensively characterized. It possibly assists in linking cellular components to ensure structural integrity or facilitate signaling processes in cells.

Pathways

C3orf10 integrates into certain cellular pathways potentially involving cytoskeleton organization or signaling cascades. It associates with proteins involved in structural support and signal relay including some members of the armadillo family known for roles in cell adhesion and signaling. However the precise pathways C3orf10 participates in remain to be fully elucidated.

C3orf10 holds interest in research related to neurodegenerative conditions and muscular disorders. Alterations in its expression or function may link to conditions like amyotrophic lateral sclerosis (ALS) or dystrophin-related muscle dysfunction. C3orf10 could interact with proteins such as dystrophin or others involved in neurodegeneration highlighting its potential impact on disease pathways.

Specifications

Form

Liquid

Additional notes

ab177597 was purified using conventional chromatography techniques.

General info

Function

Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).

Sequence similarities

Belongs to the BRK1 family.

Subcellular localisation

Cytoskeleton

Product protocols

Target data

Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).
See full target information BRK1

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