Recombinant Human C6orf115 protein is a Human Full Length protein, in the 1 to 81 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, MS.
M G S S H H H H H H S S G L V P R G S H M G S M N V D H E V N L L V E E I H R L G S K N A D G K L S V K F G V L F R D D K C A N L F E A L V G T L K A A K R R K I V T Y P G E L L L Q G V H D D V D I I L L Q D
Application | Reactivity | Dilution info | Notes |
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Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
C6orf115, HSPC280, PRO2013, ABRACL, Costars family protein ABRACL, ABRA C-terminal-like protein
Recombinant Human C6orf115 protein is a Human Full Length protein, in the 1 to 81 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, MS.
pH: 8
Constituents: 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl
ab156321 is purified using conventional chromatography techniques.
Belongs to the costars family.
C6orf115 also known as Lung Cancer Associated Protein 1 (LCAP1) is a human protein with an approximate molecular mass of 28 kDa. Researchers find its expression mainly in lung and kidney tissues. It likely plays a mechanical role in cellular structures although detailed mechanistic insights are still under investigation. Studies suggest C6orf115 may participate in cellular adhesion processes influencing how cells interact with their surroundings.
C6orf115 influences cell signaling and functional dynamics in tissues where it is expressed. Researchers do not currently recognize it as part of a larger protein complex but its presence suggests involvement in local signaling pathways. In particular it might impact processes requiring precise coordination of cellular communication such as in epithelial tissue that lines organs and structures in the body.
C6orf115 connects to the Wnt signaling pathway which plays a role in cell proliferation and differentiation. It might interact with proteins such as beta-catenin known for its impact on gene transcription in this pathway. Furthermore C6orf115 has potential interactions within the focal adhesion pathway possibly influencing proteins such as vinculin which is important for maintaining cellular structural integrity.
C6orf115 displays associations with lung cancer and kidney diseases. Altered expression levels correlate with tumor progression indicating its potential role in oncogenesis. In lung cancer interactions with proteins like epidermal growth factor receptor (EGFR) may contribute to aberrant cellular growth signals. In kidney pathologies C6orf115 presence suggests a role in maintaining normal tissue architecture though further research will better clarify these connections.
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15% SDS-PAGE analysis of ab156321 (3μg).
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