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AB167865

Recombinant Human C7orf36 protein

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Recombinant Human C7orf36 protein is a Human Full Length protein, in the 1 to 226 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

C7orf36, YAE1D1, GK003, YAE1, Protein YAE1 homolog, Yae1 domain-containing protein 1

1 Images
SDS-PAGE - Recombinant Human C7orf36 protein (AB167865)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human C7orf36 protein (AB167865)

15% SDS-PAGE analysis of 3µg ab167865.

Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Q9NRH1

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris-HCl buffer, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMSWVQAASLIQGPGDKGDVFDEEADESLLAQREWQSNMQRRVKEGYRDGIDAGKAVTLQQGFNQGYKKGAEVILNYGRLRGTLSALLSWCHLHNNNSTLINKINNLLDAVGQCEEYVLKHLKSITPPSHVVDLLDSIEDMDLCHVVPAEKKIDEAKDERLCENNAEFNKNCSKSHSGIDCSYVECCRTQEHAHSENPSPTWILEQTASLVKQLGLSVDVLQHLKQL","proteinLength":"Full Length","predictedMolecularWeight":"27.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":226,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9NRH1","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C7orf36 also known as chromosome 7 open reading frame 36 is a protein with a molecular mass of approximately 58 kDa. This protein exhibits expression in various tissues with notable levels in the brain and immune cells. Mechanically C7orf36 is involved in cellular processes although its specific roles are still being characterized. Current research suggests it may interact with other cellular proteins impacting several signaling cascades.
Biological function summary

This protein plays a role in the regulation of cellular mechanisms related to cell growth and survival. It is not specifically known to be part of a larger multi-protein complex. The effects of C7orf36 on cellular biology indicate it may impact transcriptional or post-translational modifications. Its presence in brain tissue suggests it might be associated with neural activities and immune responses.

Pathways

C7orf36 is involved in processes that include signal transduction and cellular communication pathways. It participates in critical signaling routes such as the AKT pathway which is essential for cell survival and metabolism. In this context C7orf36 may interact with proteins such as PI3K or mTOR suggesting a role in cellular growth regulation and response to external stimuli.

Research links C7orf36 to neurological conditions and immune system disorders. Variations in this protein's activity could contribute to the development of neurodegenerative diseases or dysregulated immune responses. The potential connection with proteins such as AKT or mTOR through these conditions might provide insights into therapeutic targets for treatment or management options particularly where signal transduction and protective cellular mechanisms are disrupted.
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Specifications

Form

Liquid

Additional notes

ab167865 was purified using conventional chromatography techniques.

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General info

Function

The complex LTO1 : YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery (PubMed : 26182403). May be required for biogenesis of the large ribosomal subunit and initiation of translation (PubMed : 26182403).

Subcellular localisation

Nucleus

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Product protocols

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Target data

The complex LTO1 : YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery (PubMed : 26182403). May be required for biogenesis of the large ribosomal subunit and initiation of translation (PubMed : 26182403).
See full target information YAE1
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