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AB106870

Recombinant Human Calcium binding protein 7

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Recombinant Human Calcium binding protein 7 is a Human Fragment protein, in the 1 to 188 aa range, expressed in Escherichia coli, with >80%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

CALN2, CABP7, Calcium-binding protein 7, CaBP7, Calneuron II, Calneuron-2

1 Images
SDS-PAGE - Recombinant Human Calcium binding protein 7 (AB106870)
  • SDS-PAGE

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SDS-PAGE - Recombinant Human Calcium binding protein 7 (AB106870)

15% SDS-PAGE analysis of 3μg ab106870.

Key facts

Purity

>80% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Q86V35

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: PBS

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMPFHPVTAALMYRGIYTVPNLLSEQRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEEFVTLLGPKLSTSGIPEKFHGTDFDTVFWKCDMQKLTVDELKRLLYDTFCEHLSMKDIENIIMTEEESHLGTAEECPVDVETCSNQQIRQTCVRKS","proteinLength":"Fragment","predictedMolecularWeight":"23.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":188,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q86V35","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Calcium binding protein 7 (CABP7) also known as CABP7 retains a specific function in binding calcium ions. This protein consists of a molecular mass of approximately 27 kDa and is characterized by two EF-hand motifs that facilitate its calcium-binding capability. CABP7 is expressed in various tissues including the brain and the retina where it interacts with its cellular environment to regulate calcium signaling.
Biological function summary

CABP7 modulates neuronal activities and intracellular calcium levels which impact neurotransmitter release and signal transduction processes. Although not explicitly part of a larger complex this protein influences the function of voltage-gated calcium channels impacting synaptic transmission. Its activity in neurons highlights its role in maintaining calcium homeostasis essential for various cellular processes.

Pathways

CABP7 interacts with signaling pathways such as the calcium signaling pathway and synaptic vesicle cycle. This protein affects calcium dynamics critical for neuronal communication working closely with other members of the neuronal calcium sensor family to regulate calcium entry and vesicle exocytosis. It is related to proteins like calmodulin and other calcium-binding proteins that play significant roles in these pathways supporting the transmission of signals along neurons.

CABP7 links to neurological conditions such as epilepsy and neurodegenerative diseases. Abnormal calcium signaling due to altered expression of CABP7 may contribute to these conditions where proper calcium homeostasis is important. Moreover CABP7 might interact with other proteins implicated in these diseases like synaptic proteins and other calcium-handling proteins which suggests a potential area for therapeutic intervention or biomarker discovery.
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Specifications

Form

Liquid

Additional notes

ab106870 is purified using conventional chromatography techniques.

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General info

Function

Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.

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Product protocols

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Target data

Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
See full target information CABP7
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