Recombinant Human Calreticulin protein (ab91577)

Recombinant Human Calreticulin protein is a Human Full Length protein, expressed in Escherichia coli, with >80% purity and suitable for SDS-PAGE, WB.

This product has no reviews yet! Submit a review

Alternative names=Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, HACBP, grp60, ERp60, CRTC, CALR

Reactivity data

Application	Reactivity	Dilution info	Notes
Application SDS-PAGE	Reactivity Reacts	Dilution info -	Notes -
Application WB	Reactivity Reacts	Dilution info -	Notes 50 ng of protein recommended. ab91577 can be used as a WB positive control in conjunction with ab39818.

Target data

Recombinant Human Calreticulin protein is a Human Full Length protein, expressed in Escherichia coli, with >80% purity and suitable for SDS-PAGE, WB.

Alternative names=Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, HACBP, grp60, ERp60, CRTC, CALR

Purity: >80% SDS-PAGE
Expression system: Escherichia coli
Tags: His tag N-Terminus
Applications: SDS-PAGE, WB
Biologically active: No
Accession: P27797-1
Protein length: Full Length
Animal free: No
Nature: Recombinant
Species: Human
Concentration
Storage buffer: Constituents: 5% Glycerol (glycerin, glycerine), 0.877% Sodium chloride, 0.606% Tris, 0.056% Calcium chloride

Form: Liquid
Additional notes: Purity: > 80 % full-length protein as determined by Western blot analyses

Function: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed:7876246). Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (PubMed:11149926). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity).
Sequence similarities: Belongs to the calreticulin family.
Subcellular localisation: Cytolytic granule

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com