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AB132986

Recombinant human CamKII gamma protein (GST tag N-Terminus)

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(1 Publication)

Recombinant human CamKII gamma protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 527 aa range, expressed in Wheat germ, with >99%, suitable for SDS-PAGE, ELISA, WB, FuncS.

View Alternative Names

CAMK, CAMK-II, CAMKG, CAMK2G, Calcium/calmodulin-dependent protein kinase type II subunit gamma, CaM kinase II subunit gamma, CaMK-II subunit gamma

2 Images
Functional Studies - Recombinant human CamKII gamma protein (GST tag N-Terminus) (AB132986)
  • FuncS

Unknown

Functional Studies - Recombinant human CamKII gamma protein (GST tag N-Terminus) (AB132986)

Kinase Assay using ab132986.
Fig.1 : SDS-PAGE gel
Fig.2 : Autoradiography of SDS-PAGE gel. Kinase substrates :
H3 histone, family 3A - calf thymus - Molecular weight : approx. 16.5-17 kDa on SDS-PAGE
Myelin basic protein - bovine brain - Molecular weight : approx. 21-22 kDa on SDS-PAGE
Histone H1.0 - calf thymus - Molecular weight : approx. 32-33 kDa on SDS-PAGE
Beta-casein protein- bovine milk - Molecular weight : approx. 33-34 kDa on SDS-PAGE

SDS-PAGE - Recombinant human CamKII gamma protein (GST tag N-Terminus) (AB132986)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human CamKII gamma protein (GST tag N-Terminus) (AB132986)

12.5% SDS-PAGE analysis of ab132986 stained with Coomassie Blue.

Key facts

Purity

>99%

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, FuncS, SDS-PAGE, ELISA

applications

Biologically active

Yes

Biological activity

Active

Accession

Q13555

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MATTATCTRFTDDYQLFEELGKGAFSGVRRCVKKTPTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVHLMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ","proteinLength":"Full Length","predictedMolecularWeight":"83.71 kDa","actualMolecularWeight":null,"aminoAcidEnd":527,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q13555","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
True
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Specifications

Form

Liquid

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General info

Function

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity (PubMed : 16690701). In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin (PubMed : 16690701). In the central nervous system, it is involved in the regulation of neurite formation and arborization (PubMed : 30184290). It may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity).

Sequence similarities

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

Post-translational modifications

Autophosphorylation of Thr-287 following activation by Ca(2+)/calmodulin. Phosphorylation of Thr-287 locks the kinase into an activated state.

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Product protocols

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Target data

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity (PubMed : 16690701). In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin (PubMed : 16690701). In the central nervous system, it is involved in the regulation of neurite formation and arborization (PubMed : 30184290). It may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity).
See full target information CAMK2G
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 12:e2409513 PubMed39840457

2025

CAMKIIδ Reinforces Lipid Metabolism and Promotes the Development of B Cell Lymphoma.

Applications

Unspecified application

Species

Unspecified reactive species

Jiawei Zhang,Senlin Xu,Hui Fang,Dehao Wu,Ching Ouyang,Yunfei Shi,Zhenkang Hu,Mingfeng Zhang,Yaoyao Zhong,Junwei Zhao,Yichao Gan,Shize Zhang,Xiaoqian Liu,Jie Yin,Yuan Li,Mengyue Tang,Yingda Wang,Ling Li,Wing C Chan,David Horne,Mingye Feng,Wendong Huang,Ying Gu
View all publications
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Product promise

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