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AB85484

Recombinant Human Carbonic anhydrase 2/CA2 protein (Tag Free)

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(1 Publication)

Recombinant Human Carbonic anhydrase 2/CA2 protein (Tag Free) is a Human Full Length protein, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, FuncS.

View Alternative Names

Carbonic anhydrase 2, Carbonate dehydratase II, Carbonic anhydrase C, Carbonic anhydrase II, Cyanamide hydratase CA2, CAC, CA-II, CA2

1 Images
SDS-PAGE - Recombinant Human Carbonic anhydrase 2/CA2 protein (Tag Free) (AB85484)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human Carbonic anhydrase 2/CA2 protein (Tag Free) (AB85484)

15% SDS-PAGE analysis of 3μg ab85484.

Key facts

Purity

>95% SDS-PAGE

Expression system

Escherichia coli

Tags

Tag free

Applications

FuncS, SDS-PAGE

applications

Biologically active

Yes

Biological activity

Specific activity is > 7,000pmol/min/μg, and is defined as the amount of enzyme that hydrolyze 1.0pmole of 4-nitrophenyl acetate to 4-nitrophenol per minute at pH 8.0 at 37°C.

Accession

P00918

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: PBS, 10% Glycerol (glycerin, glycerine)

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P00918","tags":[]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
True
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Specifications

Form

Liquid

Additional notes

ab85484 was purified by using conventional chromatography.

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General info

Function

Catalyzes the reversible hydration of carbon dioxide (PubMed : 11327835, PubMed : 11802772, PubMed : 11831900, PubMed : 12056894, PubMed : 12171926, PubMed : 1336460, PubMed : 14736236, PubMed : 15300855, PubMed : 15453828, PubMed : 15667203, PubMed : 15865431, PubMed : 16106378, PubMed : 16214338, PubMed : 16290146, PubMed : 16686544, PubMed : 16759856, PubMed : 16807956, PubMed : 17127057, PubMed : 17251017, PubMed : 17314045, PubMed : 17330962, PubMed : 17346964, PubMed : 17540563, PubMed : 17588751, PubMed : 17705204, PubMed : 18024029, PubMed : 18162396, PubMed : 18266323, PubMed : 18374572, PubMed : 18481843, PubMed : 18618712, PubMed : 18640037, PubMed : 18942852, PubMed : 1909891, PubMed : 1910042, PubMed : 19170619, PubMed : 19186056, PubMed : 19206230, PubMed : 19520834, PubMed : 19778001, PubMed : 7761440, PubMed : 7901850, PubMed : 8218160, PubMed : 8262987, PubMed : 8399159, PubMed : 8451242, PubMed : 8485129, PubMed : 8639494, PubMed : 9265618, PubMed : 9398308). Can also hydrate cyanamide to urea (PubMed : 10550681, PubMed : 11015219). Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (PubMed : 15990874). Essential for bone resorption and osteoclast differentiation (PubMed : 15300855). Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption.

Sequence similarities

Belongs to the alpha-carbonic anhydrase family.

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Product protocols

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Target data

Catalyzes the reversible hydration of carbon dioxide (PubMed : 11327835, PubMed : 11802772, PubMed : 11831900, PubMed : 12056894, PubMed : 12171926, PubMed : 1336460, PubMed : 14736236, PubMed : 15300855, PubMed : 15453828, PubMed : 15667203, PubMed : 15865431, PubMed : 16106378, PubMed : 16214338, PubMed : 16290146, PubMed : 16686544, PubMed : 16759856, PubMed : 16807956, PubMed : 17127057, PubMed : 17251017, PubMed : 17314045, PubMed : 17330962, PubMed : 17346964, PubMed : 17540563, PubMed : 17588751, PubMed : 17705204, PubMed : 18024029, PubMed : 18162396, PubMed : 18266323, PubMed : 18374572, PubMed : 18481843, PubMed : 18618712, PubMed : 18640037, PubMed : 18942852, PubMed : 1909891, PubMed : 1910042, PubMed : 19170619, PubMed : 19186056, PubMed : 19206230, PubMed : 19520834, PubMed : 19778001, PubMed : 7761440, PubMed : 7901850, PubMed : 8218160, PubMed : 8262987, PubMed : 8399159, PubMed : 8451242, PubMed : 8485129, PubMed : 8639494, PubMed : 9265618, PubMed : 9398308). Can also hydrate cyanamide to urea (PubMed : 10550681, PubMed : 11015219). Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (PubMed : 15990874). Essential for bone resorption and osteoclast differentiation (PubMed : 15300855). Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption.
See full target information CA2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Genomics, proteomics & bioinformatics 19:94-107 PubMed33662630

2021

Quantitative Secretome Analysis Reveals Clinical Values of Carbonic Anhydrase II in Hepatocellular Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaohua Xing,Hui Yuan,Hongzhi Liu,Xionghong Tan,Bixing Zhao,Yingchao Wang,Jiahe Ouyang,Minjie Lin,Xiaolong Liu,Aimin Huang
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