Recombinant Human Cardiac Troponin I protein
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Recombinant Human Cardiac Troponin I protein is a Human Full Length protein in the 1 to 210 aa range with >90% purity and suitable for SDS-PAGE. The predicted molecular weight of ab283299 protein is 26.4 kDa.
- Save time and ensure accurate results - use our Cardiac Troponin I (cTnI) protein as a control
View Alternative Names
TNNC1, TNNI3, Cardiac troponin I
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human Cardiac Troponin I protein (AB283299)
Analysis of ab283299 (3 μg) by SDS-PAGE (15%) under reducing condition and visualized by coomassie blue stain.
Reactivity data
Product details
Check out our protein gel staining guide for SDS-PAGE here
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Sequence similarities
Belongs to the troponin I family.
Post-translational modifications
Phosphorylated at Ser-42 and Ser-44 by PRKCE; phosphorylation increases myocardium contractile dysfunction (By similarity). Phosphorylated at Ser-23 and Ser-24 by PRKD1; phosphorylation reduces myofilament calcium sensitivity. Phosphorylated preferentially at Thr-31. Phosphorylation by STK4/MST1 alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T).
Target data
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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